Literature DB >> 12812466

The first total synthesis of nakadomarin A.

Toshiaki Nagata1, Masako Nakagawa, Atsushi Nishida.   

Abstract

(-)-Nakadomarin A is a member of manzamine alkaloid isolated from a marine sponge and have a unique hexacyclic structure. The first total synthesis of (+)-nakadomarin A, an enantiomer of natural product, has been accomplished from stereochemically defined 4-oxopiperidin-3-carboxylic acid derivative. The synthesis established the structure of nakadomarin A including absolute configuration.

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Year:  2003        PMID： 12812466     DOI： 10.1021/ja034464j

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  14 in total

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10.  Synthesis of macrocyclic natural products by catalyst-controlled stereoselective ring-closing metathesis.

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