OBJECTIVES: To determine whether women with fibromyalgia are at increased risk of developing osteoporosis or osteomalacia. METHODS: Forty premenopausal women with fibromyalgia and 37 age-matched female controls were studied. Broadband ultrasound attenuation (BUA) and velocity of sound (VOS) were measured at the calcaneum and bone mineral density was measured at the forearm and lumbar spine using dual-energy X-ray absorptiometry. Serum calcium, alkaline phosphatase, gamma-glutamyl transferase, 25-hydroxyvitamin D and plasma viscosity were measured in all subjects and parathyroid hormone was measured in subjects recruited in the latter part of the study. RESULTS: Seventeen patients with fibromyalgia syndrome and seven controls had 25-hydroxyvitamin D concentrations <20 nmol/l (P < 0.015) and in three FMS patients serum parathyroid hormone was raised. Bone density in fibromyalgia patients was slightly lower at the mid-distal forearm but comparable to that in controls at other sites. CONCLUSIONS: There is no reason to recommend routine bone densitometry in fibromyalgia patients. However, vitamin D subnutrition is common in these patients and this should be sought.
OBJECTIVES: To determine whether women with fibromyalgia are at increased risk of developing osteoporosis or osteomalacia. METHODS: Forty premenopausal women with fibromyalgia and 37 age-matched female controls were studied. Broadband ultrasound attenuation (BUA) and velocity of sound (VOS) were measured at the calcaneum and bone mineral density was measured at the forearm and lumbar spine using dual-energy X-ray absorptiometry. Serum calcium, alkaline phosphatase, gamma-glutamyl transferase, 25-hydroxyvitamin D and plasma viscosity were measured in all subjects and parathyroid hormone was measured in subjects recruited in the latter part of the study. RESULTS: Seventeen patients with fibromyalgia syndrome and seven controls had 25-hydroxyvitamin D concentrations <20 nmol/l (P < 0.015) and in three FMS patients serum parathyroid hormone was raised. Bone density in fibromyalgiapatients was slightly lower at the mid-distal forearm but comparable to that in controls at other sites. CONCLUSIONS: There is no reason to recommend routine bone densitometry in fibromyalgiapatients. However, vitamin D subnutrition is common in these patients and this should be sought.
Authors: Luis Iván Lozano-Plata; David Vega-Morales; Jorge Antonio Esquivel-Valerio; Mario Alberto Garza-Elizondo; Dionicio A Galarza-Delgado; Karina Silva-Luna; Griselda Serna-Peña; Janeth Sifuentes-Ramírez; Alfredo de Jesús Garza-Guerra; Raúl Díaz-Niño de Rivera Journal: Clin Rheumatol Date: 2021-02-10 Impact factor: 2.980
Authors: F Mateos; C Valero; J M Olmos; B Casanueva; J Castillo; J Martínez; J L Hernández; J González Macías Journal: Osteoporos Int Date: 2013-09-06 Impact factor: 4.507
Authors: Yuhree Kim; Fang Zhang; Katherine Su; Marc LaRochelle; Matthew Callahan; David Fisher; J Frank Wharam; Maryam M Asgari Journal: J Gen Intern Med Date: 2020-06-24 Impact factor: 5.128