OBJECTIVES: To investigate whether bicycle riding significantly alters total prostate-specific antigen (tPSA), free PSA (fPSA), and percent free PSA (%fPSA) serum concentrations in potential candidates for prostate cancer screening. METHODS: Thirty-three men, ranging in age from 50 to 74 years (mean 61 +/- 8), rode a 13-mile bicycle course. Blood samples for PSA analysis were drawn immediately before and 1 hour after cycling for 90 minutes. The precycling and postcycling tPSA, fPSA, and %fPSA values were compared using the Wilcoxon matched-pairs test, with P = 0.01 set as the significance level. RESULTS: Changes between precycling and postcycling values for tPSA (P = 0.517), fPSA (P = 0.048), and %fPSA (P = 0.166) were not statistically significant. CONCLUSIONS: Physical activity combined with perineal pressure as induced by a 13-mile bicycle tour has no diagnostic impact on PSA values.
OBJECTIVES: To investigate whether bicycle riding significantly alters total prostate-specific antigen (tPSA), free PSA (fPSA), and percent free PSA (%fPSA) serum concentrations in potential candidates for prostate cancer screening. METHODS: Thirty-three men, ranging in age from 50 to 74 years (mean 61 +/- 8), rode a 13-mile bicycle course. Blood samples for PSA analysis were drawn immediately before and 1 hour after cycling for 90 minutes. The precycling and postcycling tPSA, fPSA, and %fPSA values were compared using the Wilcoxon matched-pairs test, with P = 0.01 set as the significance level. RESULTS: Changes between precycling and postcycling values for tPSA (P = 0.517), fPSA (P = 0.048), and %fPSA (P = 0.166) were not statistically significant. CONCLUSIONS: Physical activity combined with perineal pressure as induced by a 13-mile bicycle tour has no diagnostic impact on PSA values.
Authors: D Jiandani; A Randhawa; R E Brown; R Hamilton; A G Matthew; J L Kuk; S M H Alibhai; E Tufts; D Santa Mina Journal: Prostate Cancer Prostatic Dis Date: 2015-05-05 Impact factor: 5.554
Authors: Zbynek Heger; Jaromir Gumulec; Ales Ondrak; Jan Skoda; Zdenek Zitka; Natalia Cernei; Michal Masarik; Ondrej Zitka; Vojtech Adam Journal: Int J Mol Sci Date: 2016-03-17 Impact factor: 5.923