Literature DB >> 12809435

A mechanism for hormesis--a problem in the wrong discipline.

A R D Stebbing1.   

Abstract

The wealth of examples of hormesis exhibiting the beta curve leave little doubt as to the generality of the phenomenon. However, its full acceptance requires a satisfactory theoretical basis to account for the diversity of instances of hormesis; without it the concept has little meaning beyond what is obvious from the defining beta curve. It has been proposed that a homeostatic hypothesis is the most plausible and is gaining support. However, there is a need to involve researchers in other disciplines than toxicology to identify physiological mechanisms to account for it, whereupon hormesis can begin to gain wider recognition and fulfill its potential in pure and applied science.

Mesh:

Year:  2003        PMID: 12809435     DOI: 10.1080/713611038

Source DB:  PubMed          Journal:  Crit Rev Toxicol        ISSN: 1040-8444            Impact factor:   5.635


  8 in total

1.  A perspective on the scientific, philosophical, and policy dimensions of hormesis.

Authors:  George R Hoffmann
Journal:  Dose Response       Date:  2009-01-19       Impact factor: 2.658

2.  Hormesis and Cellular Quality Control: A Possible Explanation for the Molecular Mechanisms that Underlie the Benefits of Mild Stress.

Authors:  F A C Wiegant; S A H de Poot; V E Boers-Trilles; A M A Schreij
Journal:  Dose Response       Date:  2012-11-16       Impact factor: 2.658

3.  Postconditioning hormesis put in perspective: an overview of experimental and clinical studies.

Authors:  F A C Wiegant; H A B Prins; R Van Wijk
Journal:  Dose Response       Date:  2010-08-12       Impact factor: 2.658

4.  Metabolomic responses to pre-chlorinated and final effluent wastewater with the addition of a sub-lethal persistent contaminant in Daphnia magna.

Authors:  Nicole D Wagner; Paul A Helm; André J Simpson; Myrna J Simpson
Journal:  Environ Sci Pollut Res Int       Date:  2019-02-04       Impact factor: 4.223

Review 5.  Similarities between the Yin/Yang Doctrine and Hormesis in Toxicology and Pharmacology.

Authors:  Haoyu Sun; Edward J Calabrese; Zhifen Lin; Baoling Lian; Xiaoxian Zhang
Journal:  Trends Pharmacol Sci       Date:  2020-06-18       Impact factor: 14.819

6.  A model for homeopathic remedy effects: low dose nanoparticles, allostatic cross-adaptation, and time-dependent sensitization in a complex adaptive system.

Authors:  Iris R Bell; Mary Koithan
Journal:  BMC Complement Altern Med       Date:  2012-10-22       Impact factor: 3.659

7.  Spexin is a novel human peptide that reduces adipocyte uptake of long chain fatty acids and causes weight loss in rodents with diet-induced obesity.

Authors:  José L Walewski; Fengxia Ge; Harrison Lobdell; Nancy Levin; Gary J Schwartz; Joseph R Vasselli; Afons Pomp; Gregory Dakin; Paul D Berk
Journal:  Obesity (Silver Spring)       Date:  2014-03-08       Impact factor: 5.002

8.  Hormetic Responses of Lonicera Japonica Thunb. To Cadmium Stress.

Authors:  Zhouli Liu; Wei Chen; Xingyuan He; Lian Jia; Shuai Yu; Mingzhu Zhao
Journal:  Dose Response       Date:  2015-05-04       Impact factor: 2.658

  8 in total

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