Literature DB >> 12808253

First natural urease inhibitor from Euphorbia decipiens.

Viqar Uddin Ahmad1, Javid Hussain, Hidayat Hussain, Amir Reza Jassbi, Farman Ullah, Muhammad Arif Lodhi, Amsha Yasin, Muhammad Iqbal Choudhary.   

Abstract

Three new diterpene esters with a myrsinol-type skeleton have been isolated from Euphorbia decipiens BOISS. & BUHSE. The structure elucidation of the isolated compounds was based primarily on two-dimensional (2D)-NMR techniques including correlation spectroscopy (COSY), heteronuclear multiple quantum coherence (HMQC), heteronuclear multiple bond correlation (HMBC) and nuclear Overhauser effect spectroscopy (NOESY) experiments. Compounds 1 and 3 are active against prolyl endopeptidase and compound 2 showed inhibitory activity against urease enzyme.

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Year:  2003        PMID： 12808253     DOI： 10.1248/cpb.51.719

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  9 in total

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2.  Antinociceptive, muscle relaxant and sedative activities of gold nanoparticles generated by methanolic extract of Euphorbia milii.

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3.  Screening of 20 commonly used Iranian traditional medicinal plants against urease.

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Journal:  Iran J Pharm Res       Date:  2014       Impact factor: 1.696

4.  A preliminary investigation of the jack-bean urease inhibition by randomly selected traditionally used herbal medicine.

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5.  Structural basis of binding and rationale for the potent urease inhibitory activity of biscoumarins.

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Journal:  Biomed Res Int       Date:  2014-09-09       Impact factor: 3.411

Review 6.  An overview on the potential of natural products as ureases inhibitors: A review.

Authors:  Luzia V Modolo; Aline X de Souza; Lívia P Horta; Débora P Araujo; Ângelo de Fátima
Journal:  J Adv Res       Date:  2014-10-13       Impact factor: 10.479

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Journal:  Heliyon       Date:  2019-08-02

8.  Investigation of Euphorbia nivulia-HAM for Enzyme Inhibition Potential in Relation to the Phenolic and Flavonoid Contents and Radical Scavenging Activity.

Authors:  Muhammad Younus; Muhammad Mohtasheem-Ul-Hasan; Shakeel Ijaz; Muhammad Kamran; Ambreen Maqsood; Bushra Saddique; Uzair Nisar; Muhammad Ashraf; Eman A Mahmoud; Ahmed M El-Sabrout; Hosam O Elansary
Journal:  Life (Basel)       Date:  2022-02-21

9.  Urease Inhibitory Activities of some Commonly Consumed Herbal Medicines.

Authors:  Shabnam Mahernia; Kowsar Bagherzadeh; Faraz Mojab; Massoud Amanlou
Journal:  Iran J Pharm Res       Date:  2015       Impact factor: 1.696
  9 in total

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