Literature DB >> 12807350

Mechanisms of troglitazone hepatotoxicity.

Martyn T Smith1.   

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Year:  2003        PMID： 12807350     DOI： 10.1021/tx034033e

Source DB:  PubMed          Journal:  Chem Res Toxicol        ISSN： 0893-228X            Impact factor:   3.739


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  32 in total

1.  Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4α transduction.

Authors:  Kazuo Takayama; Mitsuru Inamura; Kenji Kawabata; Kazufumi Katayama; Maiko Higuchi; Katsuhisa Tashiro; Aki Nonaka; Fuminori Sakurai; Takao Hayakawa; Miho Kusuda Furue; Hiroyuki Mizuguchi
Journal:  Mol Ther       Date:  2011-11-08       Impact factor: 11.454

2.  Editorial: Closing sale of innovative treatment options for the treatment of diabetes and metabolic disorders?

Authors:  Christoph Schindler
Journal:  Ther Adv Endocrinol Metab       Date:  2011-12       Impact factor: 3.565

3.  Chemical proteomics-based analysis of off-target binding profiles for rosiglitazone and pioglitazone: clues for assessing potential for cardiotoxicity.

Authors:  Brian R Hoffmann; Mohamed F El-Mansy; Daniel S Sem; Andrew S Greene
Journal:  J Med Chem       Date:  2012-09-28       Impact factor: 7.446

4.  Hepatocellular exposure of troglitazone metabolites in rat sandwich-cultured hepatocytes lacking Bcrp and Mrp2: interplay between formation and excretion.

Authors:  Kyunghee Yang; Kim L R Brouwer
Journal:  Drug Metab Dispos       Date:  2014-05-05       Impact factor: 3.922

5.  Differences in hepatotoxicity and gene expression profiles by anti-diabetic PPAR gamma agonists on rat primary hepatocytes and human HepG2 cells.

Authors:  Lei Guo; Lu Zhang; Yongming Sun; Levan Muskhelishvili; Ernice Blann; Stacey Dial; Leming Shi; Gary Schroth; Yvonne P Dragan
Journal:  Mol Divers       Date:  2006-09-21       Impact factor: 2.943

Review 6.  Assessing health risks from multiple environmental stressors: Moving from G×E to I×E.

Authors:  Cliona M McHale; Gwendolyn Osborne; Rachel Morello-Frosch; Andrew G Salmon; Martha S Sandy; Gina Solomon; Luoping Zhang; Martyn T Smith; Lauren Zeise
Journal:  Mutat Res Rev Mutat Res       Date:  2017-11-24       Impact factor: 5.657

7.  Rapid LC-MS drug metabolite profiling using microsomal enzyme bioreactors in a parallel processing format.

Authors:  Besnik Bajrami; Linlin Zhao; John B Schenkman; James F Rusling
Journal:  Anal Chem       Date:  2009-12-15       Impact factor: 6.986

8.  Role of biotransformation in 3-(3,5-dichlorophenyl)-2,4-thiazolidinedione-induced hepatotoxicity in Fischer 344 rats.

Authors:  Christine M Crincoli; Niti N Patel; Ruy Tchao; Peter J Harvison
Journal:  Toxicology       Date:  2008-06-25       Impact factor: 4.221

9.  Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes.

Authors:  Lyudmila I Rachek; Larysa V Yuzefovych; Susan P Ledoux; Neil L Julie; Glenn L Wilson
Journal:  Toxicol Appl Pharmacol       Date:  2009-07-24       Impact factor: 4.219

Review 10.  Technical pitfalls and improvements for high-speed screening and QSAR analysis to predict inhibitors of the human bile salt export pump (ABCB11/BSEP).

Authors:  Hikaru Saito; Masako Osumi; Hiroyuki Hirano; Wangsoo Shin; Ryota Nakamura; Toshihisa Ishikawa
Journal:  AAPS J       Date:  2009-08-18       Impact factor: 4.009
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