| Literature DB >> 1280543 |
M Dalrymple-Hay1, R Aitchison, P Collins, M Sekhar, B Colvin.
Abstract
Hydroxyethyl starch (HES) (Hespan, DuPont) is a widely used synthetic volume expander which in standard doses of up to 1.5l in 24 h has no significant effect on coagulation (Munsch et al. 1988). However, the data sheet states that in large volumes HES may alter the coagulation mechanism. We now report a case of HES induced acquired von Willebrand's disease (vWD) in which severe bleeding occurred.Entities:
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Year: 1992 PMID： 1280543 DOI： 10.1111/j.1365-2257.1992.tb00367.x
Source DB: PubMed Journal: Clin Lab Haematol ISSN： 0141-9854