Effects of serial visuomotor tasks on contingent negative variation.

We evaluated contingent negative variation (CNV) in 15 right-handed normal subjects who performed simple finger extension(NB) or skilled finger movement task with visual guidance (B). When subjects performed serial tasks of NB-B1 (first block of B)-B2 (second block of B), the CNV amplitudes were larger in BI compared with NB at the left frontoparietal leads for early CNV, at widely distributed areas for the middle CNV and at the left frontopatietal and right frontal leads for late CNV. The present results suggest that the frontoparietal area involving the prefrontal and sensorimotor cortices, plays an important role in visuomotor learning.