Literature DB >> 12802473

[Beta-radiation exposure at the finger tips during the radionuclide synovectomy].

K Liepe1, M Andreeff, J Mielcarek, I Barth, G Wunderlich, J Kropp, J Kotzerke.   

Abstract

AIM: The radiation synovectomy is a widespread therapeutic option in rheumatoid arthritis. However, data for the beta-radiation exposure are rare. The aim of this study was to determine the personal dose equivalent H(P) (0.07) of the skin of the hands.
METHODS: Thermo-luminescence detectors (TLDs) were attached at all fingertips of the therapist, the radiochemist and the nurse. In summary, the measurement of beta-exposure occurred in 155 joints at 6 days with different radio-nuclides ((169)Er, (186)Re, (90)Y).
RESULTS: The greatest beta exposure were show at the forefinger (L-Ff) and thumb (L-Th) of the left hand, with which the therapist (right hander) fixed the injection needle. In 52 treated finger-joints (1204 MBq (169)Er), 29 treated large joints (2405 MBq (186)Re) and 15 treated knees (3100 MBq (90)Y) we found a cumulative beta exposure over all radionuclides of 190 mSv at L-Ff and 48 mSv at L-Th. The specific beta exposure for the individual radio-nuclides showed beta exposures of 0.56 mu Sv/MBq for (169)Er and 1.52 mu Sv/MBq for (186)Re-186 at the L-Ff. With using a manipulator the beta-exposure ((90)Y) could reduced from 22,09 to 0.42 mu Sv/MBq at the L-Ff. The greatest beta exposures for the radiochemist was 119 mSv at the L-Ff for all radionuclides.
CONCLUSION: In usual techniques of radiation synovectomy the (90)Y produced the greatest part of radiation exposure. Especially at the L-Ff it might exceed the German limit for the official dosimetry service at the skin ( section sign 55 Strl-SchV). Using a holding forceps we can keep the legal rules and can reduce considerably the beta exposure.

Entities:  

Mesh:

Substances:

Year:  2003        PMID: 12802473

Source DB:  PubMed          Journal:  Nuklearmedizin        ISSN: 0029-5566            Impact factor:   1.379


  2 in total

1.  Radiation Synovectomy: an effective alternative treatment for inflamed small joints.

Authors:  N Karavida; A Notopoulos
Journal:  Hippokratia       Date:  2010-01       Impact factor: 0.471

Review 2.  Radiosynovectomy in the therapeutic management of arthritis.

Authors:  Liepe Knut
Journal:  World J Nucl Med       Date:  2015 Jan-Apr
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.