Literature DB >> 1280229

Epitope mapping of two isoforms of a trans Golgi network specific integral membrane protein TGN38/41.

A Wilde1, B Reaves, G Banting.   

Abstract

TGN38/41 is an integral membrane protein predominantly located in the trans Golgi network (TGN) of rat (NRK) cells. We have used a cDNA expression system to map the epitopes recognised by a panel of antibodies raised to TGN38/41 as a preliminary step in the accurate identification of the region(s) of the molecule responsible for its correct intracellular location. These studies have confirmed the predicted topology of the molecule, and have identified a region in the cytoplasmic domain which is immunologically (and hence potentially functionally) conserved between species.

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Year:  1992        PMID： 1280229     DOI： 10.1016/0014-5793(92)81199-v

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  17 in total

1.  MAL, an integral element of the apical sorting machinery, is an itinerant protein that cycles between the trans-Golgi network and the plasma membrane.

Authors:  R Puertollano; M A Alonso
Journal:  Mol Biol Cell       Date:  1999-10       Impact factor: 4.138

2.  PAQR10 and PAQR11 mediate Ras signaling in the Golgi apparatus.

Authors:  Ting Jin; Qiurong Ding; Heng Huang; Daqian Xu; Yuhui Jiang; Ben Zhou; Zhenghu Li; Xiaomeng Jiang; Jing He; Weizhong Liu; Yixuan Zhang; Yi Pan; Zhenzhen Wang; Walter G Thomas; Yan Chen
Journal:  Cell Res       Date:  2011-10-04       Impact factor: 25.617

3.  Efficient trafficking of TGN38 from the endosome to the trans-Golgi network requires a free hydroxyl group at position 331 in the cytosolic domain.

Authors:  E P Roquemore; G Banting
Journal:  Mol Biol Cell       Date:  1998-08       Impact factor: 4.138

4.  Dendritic and postsynaptic protein synthetic machinery.

Authors:  A Gardiol; C Racca; A Triller
Journal:  J Neurosci       Date:  1999-01-01       Impact factor: 6.167

5.  The translocation, folding, assembly and redox-dependent degradation of secretory and membrane proteins in semi-permeabilized mammalian cells.

Authors:  R Wilson; A J Allen; J Oliver; J L Brookman; S High; N J Bulleid
Journal:  Biochem J       Date:  1995-05-01       Impact factor: 3.857

6.  Analysis of the co-localization of the insulin-responsive glucose transporter (GLUT4) and the trans Golgi network marker TGN38 within 3T3-L1 adipocytes.

Authors:  S Martin; B Reaves; G Banting; G W Gould
Journal:  Biochem J       Date:  1994-06-15       Impact factor: 3.857

7.  Intracellular trafficking and localization of the pseudorabies virus Us9 type II envelope protein to host and viral membranes.

Authors:  A D Brideau; T del Rio; E J Wolffe; L W Enquist
Journal:  J Virol       Date:  1999-05       Impact factor: 5.103

8.  Endocytosed cation-independent mannose 6-phosphate receptor traffics via the endocytic recycling compartment en route to the trans-Golgi network and a subpopulation of late endosomes.

Authors:  Sharron X Lin; William G Mallet; Amy Y Huang; Frederick R Maxfield
Journal:  Mol Biol Cell       Date:  2003-10-31       Impact factor: 4.138

9.  Okadaic acid treatment leads to a fragmentation of the trans-Golgi network and an increase in expression of TGN38 at the cell surface.

Authors:  M Horn; G Banting
Journal:  Biochem J       Date:  1994-07-01       Impact factor: 3.857

10.  TGN38/41 recycles between the cell surface and the TGN: brefeldin A affects its rate of return to the TGN.

Authors:  B Reaves; M Horn; G Banting
Journal:  Mol Biol Cell       Date:  1993-01       Impact factor: 4.138
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