Literature DB >> 12800912

Simple approach to the radiated scalp wound using INTEGRA skin substitute.

Denis L Gonyon1, Michael R Zenn.   

Abstract

The chronic irradiated scalp wound remains one of the most difficult reconstructions for the plastic surgeon. With its inherent radiodermatitis and poor healing potential, chronic ulcers down to bone will result if coverage cannot be achieved. Reconstructive procedures as simple as a skin graft have a high complication rate in the irradiated wound and often fail. Local tissue transfer also has a high failure and complication rate because of the decreased vascularity of the wound bed and radiation damage to the surrounding scalp tissue, limiting its manipulation. The authors report two cases using a simple method with INTEGRA bilaminate skin substitute (Integra Life Sciences, Plainsboro, NJ) for repair of difficult wounds of the radiated scalp. Case one involves a patient with nonhealing radiation ulcers that had failed local wound care, hyperbaric oxygen, and split-thickness skin grafting. Case two involves a patient with extensive squamous cell cancer of the scalp that recurred despite total scalp radiation, requiring resection of more than 50% of the total surface area of the scalp. Both these patients were successfully treated using INTEGRA artificial skin substitute (Integra Life Sciences). This simple method using INTEGRA (Integra Life Sciences) resulted in complete healing of the radiated scalp wound and an acceptable, functional, and cosmetic outcome with minimal morbidity to the patients.

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Mesh:

Year:  2003        PMID: 12800912     DOI: 10.1097/01.sap.0000046788.45508.a3

Source DB:  PubMed          Journal:  Ann Plast Surg        ISSN: 0148-7043            Impact factor:   1.539


  8 in total

Review 1.  Radiotherapy and wound healing.

Authors:  Emma-Louise Dormand; Paul E Banwell; Timothy E E Goodacre
Journal:  Int Wound J       Date:  2005-06       Impact factor: 3.315

Review 2.  Technical Refinements with the Use of Biologic Healing Agents.

Authors:  Rami P Dibbs; Monal Depani; James F Thornton
Journal:  Semin Plast Surg       Date:  2022-02-25       Impact factor: 2.195

Review 3.  Use of Biologic Agents in Nasal and Scalp Reconstruction.

Authors:  Monal Depani; Andrew E Grush; Matthew J Parham; Lloyd M Jones; James F Thornton
Journal:  Semin Plast Surg       Date:  2022-03-09       Impact factor: 2.195

Review 4.  Infectious Complications Associated with the Use of Integra: A Systematic Review of the Literature.

Authors:  Santiago R Gonzalez; Keith G Wolter; James C Yuen
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-07-15

5.  Single-stage full-thickness scalp reconstruction using acellular dermal matrix and skin graft.

Authors:  Yoon S Chun; Kapil Verma
Journal:  Eplasty       Date:  2011-01-25

6.  The use of acellular dermal matrix for coverage of exposed joint and extensor mechanism in thermally injured patients with few options.

Authors:  Dhaval Bhavsar; Mayer Tenenhaus
Journal:  Eplasty       Date:  2008-06-24

7.  Integra-based Reconstruction of Large Scalp Wounds: A Case Report and Systematic Review of the Literature.

Authors:  Maxwell B Johnson; Alex K Wong
Journal:  Plast Reconstr Surg Glob Open       Date:  2016-10-24

Review 8.  Review of History of Basic Principles of Burn Wound Management.

Authors:  Hyunjin Kim; Seongmee Shin; Donghoon Han
Journal:  Medicina (Kaunas)       Date:  2022-03-07       Impact factor: 2.430

  8 in total

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