OBJECTIVE: We wanted to assess possible alterations in brain activation in PTSD patients with severe hyperarousal symptoms and impulsive aggressiveness. METHOD: 25 Croatian War (1991-1995) veterans with combat-related PTSD with severe hyperarousal symptoms and impulsive aggressiveness were assessed for possible alterations in cerebral blood flow in single photon emission computed tomography brain scans. RESULTS: Increased regional cerebral blood flow in projection area of nucleus accumbens was found in 13 of 25 subjects, and for all in the dominant brain hemisphere. DISCUSSION: We believe that at least some of PTSD symptoms, and especially the impulsive aggression, can be associated with increased regional cerebral blood flow in the projection area of nucleus accumbens.
OBJECTIVE: We wanted to assess possible alterations in brain activation in PTSDpatients with severe hyperarousal symptoms and impulsive aggressiveness. METHOD: 25 Croatian War (1991-1995) veterans with combat-related PTSD with severe hyperarousal symptoms and impulsive aggressiveness were assessed for possible alterations in cerebral blood flow in single photon emission computed tomography brain scans. RESULTS: Increased regional cerebral blood flow in projection area of nucleus accumbens was found in 13 of 25 subjects, and for all in the dominant brain hemisphere. DISCUSSION: We believe that at least some of PTSD symptoms, and especially the impulsive aggression, can be associated with increased regional cerebral blood flow in the projection area of nucleus accumbens.
Authors: Robert Christian Wolf; Philipp Arthur Thomann; Fabio Sambataro; Nenad Vasic; Markus Schmid; Nadine Donata Wolf Journal: Eur Arch Psychiatry Clin Neurosci Date: 2012-03-11 Impact factor: 5.270
Authors: Elizabeth E Van Voorhees; Daniel A Moore; Nathan A Kimbrel; Eric A Dedert; Kirsten H Dillon; Eric B Elbogen; Patrick S Calhoun Journal: Rehabil Psychol Date: 2018-02
Authors: Derrick L Nehrenberg; Ramona M Rodriguiz; Michel Cyr; Xiaodong Zhang; Jean M Lauder; Jean-Louis Gariépy; William C Wetsel Journal: Behav Brain Res Date: 2009-02-21 Impact factor: 3.332