| Literature DB >> 12799024 |
K-M Myhr1, K S Vågnes, T H Marøy, J H Aarseth, H I Nyland, C A Vedeler.
Abstract
Interleukin-10 (IL-10) may have both pro- and anti-inflammatory effects in Guillain-Barré syndrome (GBS). The distribution of polymorphisms in the IL-10 gene (-1082 (G/A), -819 (T/C) and -592 (A/C)) was analysed to determine whether they could influence disease susceptibility or clinical course in GBS. The -592 CC and -819 CC genotypes associated with increased IL-10 response were more frequent in the GBS patients than in the controls (P=0.027), but the polymorphisms did not influence the clinical course of the disease.Entities:
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Year: 2003 PMID： 12799024 DOI： 10.1016/s0165-5728(03)00133-4
Source DB: PubMed Journal: J Neuroimmunol ISSN： 0165-5728 Impact factor: 3.478