Literature DB >> 12798748

Delay in diagnosis of soft tissue sarcomas.

F Brouns1, M Stas, I De Wever.   

Abstract

AIM: We reviewed 100 patients referred with soft tissue sarcoma between May 1999 to determine doctor- and patient-related delay.
METHODS: Patient delay is defined as longer than one month from first symptoms till doctor's visit, doctor delay as longer than one month from first visit till definitive diagnosis. Sixty-eight patients had a multifactional delay.
RESULTS: Forty-seven patients showed patient delay, with a median patient delay of 4 months, ranging from 2 to 240 months. The main reason for this delay is a painless mass that is mostly ignored. When pain is present, median patient delay is shorter.Twenty-seven patients experienced doctor delay, ranging from 2 to 79 months, with a median of 6 months. The most frequent reason was a misdiagnosis from the outset, on a clinical basis only, or due to a wrong diagnosis on ultrasound. Only two of these 27 patients had a biopsy, showing a benign tumour. High grade tumours are diagnosed earlier, 85% within 6 months.
CONCLUSIONS: Delay in diagnosis of soft tissue sarcomas is still a problem requiring better patient and doctor education.

Entities:  

Mesh:

Year:  2003        PMID: 12798748     DOI: 10.1016/s0748-7983(03)00006-4

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN: 0748-7983            Impact factor:   4.424


  25 in total

1.  Trends in presentation of bone and soft tissue sarcomas over 25 years: little evidence of earlier diagnosis.

Authors:  G M Smith; G D Johnson; R J Grimer; S Wilson
Journal:  Ann R Coll Surg Engl       Date:  2011-10       Impact factor: 1.891

2.  Soft tissue tumours of the extremities.

Authors:  Ken Mannan; T W Briggs
Journal:  BMJ       Date:  2005-09-17

3.  Giant subcutaneous synovial sarcoma: an interesting case.

Authors:  Pankaj Kumar Garg; Debajyoti Mohnaty; Bhupendra Kumar Jain; Sunny Goel; Bharat Singh
Journal:  J Clin Diagn Res       Date:  2013-12-15

4.  Retrospective analysis of the impact of symptom duration on prognosis in soft tissue sarcoma.

Authors:  A Saithna; P B Pynsent; R J Grimer
Journal:  Int Orthop       Date:  2007-03-22       Impact factor: 3.075

5.  Length of symptoms before referral: prognostic variable for high-grade soft tissue sarcoma?

Authors:  Bruce T Rougraff; Jackie Lawrence; Kenneth Davis
Journal:  Clin Orthop Relat Res       Date:  2012-03       Impact factor: 4.176

6.  Perioperative outcome in sarcoma surgery.

Authors:  Moritz N Wente; Matthias H M Schwarzbach; Ulf Hinz; Christine Leowardi; Gunhild Mechtersheimer; Robert Krempien; Gerlinde Egerer; Helmut Friess; Markus W Büchler
Journal:  Langenbecks Arch Surg       Date:  2006-11-28       Impact factor: 3.445

7.  Biopsy of tumors of the musculoskeletal system.

Authors:  Jürgen Bruns; Günter Delling; Doris Henne-Bruns; Dieter K Hossfeld
Journal:  Dtsch Arztebl Int       Date:  2008-07-04       Impact factor: 5.594

8.  Territorial inequalities in management and conformity to clinical guidelines for sarcoma patients: an exhaustive population-based cohort analysis in the Rhône-Alpes region.

Authors:  Pierre Etienne Heudel; Philippe Cousin; Antoine Lurkin; Claire Cropet; Françoise Ducimetiere; Olivier Collard; Guy De Laroche; Pierre Biron; Pierre Meeus; Philippe Thiesse; Christophe Bergeron; Gualter Vaz; François Mithieux; Fadila Farsi; Yohan Fayet; François-Noel Gilly; Dominic Cellier; Jean-Yves Blay; Isabelle Ray-Coquard
Journal:  Int J Clin Oncol       Date:  2013-08-10       Impact factor: 3.402

Review 9.  [Diagnosis and therapy of soft tissue sarcomas of the extremities].

Authors:  S Bachmann; M Panzica; U Brunnemer; V Stueber; F Länger; A Kaltenborn; H Schrem; H Bektaş
Journal:  Chirurg       Date:  2013-07       Impact factor: 0.955

Review 10.  Molecular mechanisms underpinning sarcomas and implications for current and future therapy.

Authors:  Victoria Damerell; Michael S Pepper; Sharon Prince
Journal:  Signal Transduct Target Ther       Date:  2021-06-30
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