| Literature DB >> 12798332 |
Fuk Wah Sum1, Victoria Wong, Stella Han, Elwood Largis, Ruth Mulvey, Jeff Tillett.
Abstract
Piperidine, pyrrolidine, and azetidine sulfonamides were examined as linkers in designing novel human beta(3) adrenergic receptor (beta(3)-AR) agonists. The azetidine derivative 37, and piperidine derivatives 7, 8, and 13 were found to be potent beta(3)-AR agonists and have good selectivity against beta(1)- and beta(2)-AR.Entities:
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Year: 2003 PMID： 12798332 DOI： 10.1016/s0960-894x(03)00387-1
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823