| Literature DB >> 12798313 |
N G J Delaet1, L A Robinson, D M Wilson, R W Sullivan, E K Bradley, S M Dankwardt, R L Martin, H E Van Wart, K A M Walker.
Abstract
The parallel synthesis of novel inhibitors of procollagen C-terminal proteinase is described. The synthetic strategy allowed for the facile synthesis of a large number of side-chain diversified diamino acid hydroxamates, of which the D-diaminopropionic acid derivatives were shown to be single digit nanomolar PCP inhibitors.Entities:
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Year: 2003 PMID: 12798313 DOI: 10.1016/s0960-894x(03)00404-9
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823