Literature DB >> 12798258

Depression and suicidal behavior in adolescent inpatients with obsessive compulsive disorder.

Alan Apter1, Netta Horesh, Doron Gothelf, Gil Zalsman, Zippy Erlich, Noam Soreni, Abraham Weizman.   

Abstract

BACKGROUND: To investigate the prevalence and correlations of suicidal behavior in obsessive compulsive disorder (OCD) among adolescent psychiatric inpatients.
METHODS: A total of 348 adolescents, representing consecutive admissions to an adolescent inpatient unit, were assessed. Of these, 40 patients had OCD, 118 had schizophrenia, 59 had an affective disorder, 81 had a conduct disorder and 50 had an eating disorder. In addition, 87 normal community controls were assessed. All subjects were assessed for suicidal behavior by the Childhood Suicide Potential Scale (CSPS), for depression by the Beck Depression Inventory, for impulsiveness by the Impulse Control Scale, for anxiety by the State-Trait Anxiety Scale and for aggression by the Yudowsky Overt Aggression Scale.
RESULTS: All the psychiatrically ill subjects, including those with OCD, had high levels of depression, anxiety and impulsiveness, which were far higher than those of the controls. The rate of attempted suicide was, however, much lower in the OCD subjects. In addition, there was a significant inverse correlation between suicidal behavior levels on the CSPS and depression in the OCD subjects, while all other subjects showed the expected significant positive correlation between level of suicidal behavior and depression. LIMITATIONS: This study looked at a referred population and generalization to outpatient and community samples cannot be made. Distinguishing between the primary and the comorbid diagnosis is difficult and some findings are based on small sample size and therefore may be vulnerable to type I error.
CONCLUSIONS: Although suicidal ideation and depressive symptoms are common in OCD adolescent inpatients, they seem to be protected against suicide attempts. The inverse relationship between suicidal behavior and depression may mean that suicidal behavior is, in some ways, qualitatively different from that seen in other psychiatrically ill adolescents.

Entities:  

Mesh:

Year:  2003        PMID: 12798258     DOI: 10.1016/s0165-0327(02)00038-1

Source DB:  PubMed          Journal:  J Affect Disord        ISSN: 0165-0327            Impact factor:   4.839


  11 in total

1.  Frequency and correlates of suicidal ideation in pediatric obsessive-compulsive disorder.

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2.  Directionality of change in obsessive compulsive disorder (OCD) and suicidal ideation over six years in a naturalistic clinical sample.

Authors:  Lily A Brown; Emily Wakschal; Stefanie Russman-Block; Christina L Boisseau; Maria C Mancebo; Jane L Eisen; Steven A Rasmussen
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3.  Which factors may differentiate lifetime suicide attempters from ideators in obsessive-compulsive disorder patients?

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5.  SSRI versus bupropion effects on symptom clusters in suicidal depression: post hoc analysis of a randomized clinical trial.

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7.  Suicide Risk in Obsessive-Compulsive Disorder and Exploration of Risk Factors: A Systematic Review.

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8.  Family and School Contexts as Predictors of Suicidal Behavior among Adolescents: The Role of Depression and Anxiety.

Authors:  Nicolás Ruiz-Robledillo; Rosario Ferrer-Cascales; Natalia Albaladejo-Blázquez; Miriam Sánchez-SanSegundo
Journal:  J Clin Med       Date:  2019-11-24       Impact factor: 4.241

9.  Psychache and Suicidal History in Patients with Obsessive-Compulsive Disorder.

Authors:  Mehmet Emin Demirkol; Zeynep Namlı; Özge Eriş Davul; Mahmut Onur Karaytuğ; Lut Tamam; Hamdi Yılmaz
Journal:  Neuropsychiatr Dis Treat       Date:  2019-12-24       Impact factor: 2.570

10.  Frequency and severity of obsessive-compulsive symptoms/disorders, violence and suicidal in schizophrenic patients.

Authors:  S H Hosseini; M Zarghami; S Moudi; A R Mohammadpour
Journal:  Iran Red Crescent Med J       Date:  2012-06-30       Impact factor: 0.611

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