Literature DB >> 12798042

Hidden Markov models and optimized sequence alignments.

L Smith1, L Yeganova, W J Wilbur.   

Abstract

We present a formulation of the Needleman-Wunsch type algorithm for sequence alignment in which the mutation matrix is allowed to vary under the control of a hidden Markov process. The fully trainable model is applied to two problems in bioinformatics: the recognition of related gene/protein names and the alignment and scoring of homologous proteins.

Mesh:

Year:  2003        PMID: 12798042     DOI: 10.1016/s1476-9271(02)00096-8

Source DB:  PubMed          Journal:  Comput Biol Chem        ISSN: 1476-9271            Impact factor:   2.877


  3 in total

1.  Identification of related gene/protein names based on an HMM of name variations.

Authors:  L Yeganova; L Smith; W J Wilbur
Journal:  Comput Biol Chem       Date:  2004-04       Impact factor: 2.877

2.  Recent applications of Hidden Markov Models in computational biology.

Authors:  Khar Heng Choo; Joo Chuan Tong; Louxin Zhang
Journal:  Genomics Proteomics Bioinformatics       Date:  2004-05       Impact factor: 7.691

3.  Development of query strategies to identify a histologic lymphoma subtype in a large linked database system.

Authors:  Michael Graiser; Susan G Moore; Rochelle Victor; Ashley Hilliard; Leroy Hill; Michael S Keehan; Christopher R Flowers
Journal:  Cancer Inform       Date:  2007-05-04
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.