| Literature DB >> 12798040 |
Nicolas Luc1, Jean-Loup Risler, Anne Bergeron, Mathieu Raffinot.
Abstract
This paper describes an efficient algorithm based on a new concept called gene team for detecting conserved gene clusters among an arbitrary number of chromosomes. Within the clusters, neither the order of the genes nor their orientation need be conserved. In addition, insertion of foreign genes within the clusters are permitted to a user-defined extent. This algorithm has been implemented in a publicly available TEAM software that proves to be an efficient tool for systematic searches of conserved gene clusters. Examples of actual biological results are provided. The software is downloadable from http://www-igm.univ-mlv.fr/ approximately raffinot/geneteam.html.Mesh:
Year: 2003 PMID: 12798040 DOI: 10.1016/s1476-9271(02)00097-x
Source DB: PubMed Journal: Comput Biol Chem ISSN: 1476-9271 Impact factor: 2.877