Positive pressure mechanical ventilation.

There have been numerous advances in the application of positive pressure mechanical ventilation in the last two decades. As knowledge of pulmonary physiology expands, the application of modes and parameters to maximize the efficacy and minimize the complications of ventilatory support continues to advance. As the use of noninvasive ventilation becomes more widespread, its usefulness in certain clinical entities such as COPD exacerbations and acute cardiogenic pulmonary edema will become more prominent. The role of specific modes and parameters of these devices likely will be further refined to maximize outcomes.