Literature DB >> 12793311

Neurocysticercosis--New Millennium, ancient disease and unending debate.

G Narula1, K S Bawa.   

Abstract

A spurt of cases of Neurocysticercosis (NCC) at our department reopened the debate on whether to treat or not and spurred us on to review the available literature for a viable solution. Despite the disease having been around for centuries a cogent treatment plan eludes us even as other ancient scources have been successfully engaged. Neurocysticercosis presents a peculiar problem as it is an end-stage infection, accidental in man, with a benign natural course and would have merited considerably less attention, had it not chosen to infest the brain. These unique and characteristic features are the fundamental reasons why so many different treatment strategies are continuously proffered; many or none seem to work, depending on the viewpoint. And the target organs of this otherwise unglamorous tapeworm cyst--the brain, eye and spinal cord-ensure that there is always pressure, and temptation to treat rather than let it be, even if the weight of evidence is to the contrary. An overview of the history of the disease and the most recent happenings is presented here, in which these issues are reviewed with special attention to the debate on treatment. From the facts that emerge, an attempt has been made to present a workable plan that would help practicing pediatricians in treating most encountered cases till such time we hear the last word on the issue.

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Year:  2003        PMID: 12793311     DOI: 10.1007/bf02723590

Source DB:  PubMed          Journal:  Indian J Pediatr        ISSN: 0019-5456            Impact factor:   1.967


  36 in total

Review 1.  Treatment of brain cysticercosis.

Authors:  J Sotelo
Journal:  Surg Neurol       Date:  1997-08

Review 2.  Taenia solium cysticercosis: host-parasite interactions and the immune response.

Authors:  A C White; P Robinson; R Kuhn
Journal:  Chem Immunol       Date:  1997

3.  [Neurocysticercosis in children: clinical and radiological analysis and prognostic factors in 54 patients].

Authors:  O H del Brutto
Journal:  Rev Neurol       Date:  1997-11       Impact factor: 0.870

4.  Serological diagnosis of human cysticercosis by use of recombinant antigens from Taenia solium cysticerci.

Authors:  K Hubert; A Andriantsimahavandy; A Michault; M Frosch; F A Mühlschlegel
Journal:  Clin Diagn Lab Immunol       Date:  1999-07

5.  Treating neurocysticercosis medically: a systematic review of randomized, controlled trials.

Authors:  R Salinas; C Counsell; K Prasad; H Gelband; P Garner
Journal:  Trop Med Int Health       Date:  1999-11       Impact factor: 2.622

6.  [A short praziquantel regimen for the treatment of parenchymatous neurocysticercosis].

Authors:  T Corona; R Lugo; R Medina; J Sotelo
Journal:  Gac Med Mex       Date:  1999 Jul-Aug       Impact factor: 0.302

7.  Magnitude of the disease burden from neurocysticercosis in a developing country.

Authors:  C Bern; H H Garcia; C Evans; A E Gonzalez; M Verastegui; V C Tsang; R H Gilman
Journal:  Clin Infect Dis       Date:  1999-11       Impact factor: 9.079

8.  Is the course of neurocysticercosis modified by treatment with antihelminthic agents?

Authors:  A Carpio; F Santillán; P León; C Flores; W A Hauser
Journal:  Arch Intern Med       Date:  1995-10-09

Review 9.  Pharmacokinetic optimisation of the treatment of neurocysticercosis.

Authors:  J Sotelo; H Jung
Journal:  Clin Pharmacokinet       Date:  1998-06       Impact factor: 6.447

Review 10.  Extraparenchymal neurocysticercosis: report of five cases and review of management.

Authors:  J C Bandres; A C White; T Samo; E C Murphy; R L Harris
Journal:  Clin Infect Dis       Date:  1992-11       Impact factor: 9.079

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