E Planells1, C Sánchez, M A Montellano, J Mataix, J Llopis. 1. Department of Physiology, Institute of Nutrition and Food Technology (INTA), University of Granada, C/Ramón y Cajal 4, E-18071 Granada, Spain.
Abstract
OBJECTIVE: To assess the nutritional status for vitamins B(6) and B(12) and folate in an adult Mediterranean population, in order to identify patterns of intake, groups at risk for deficiency, and factors that might influence this risk. DESIGN: A cross-sectional epidemiological survey. SETTING: Andalusia, a western Mediterranean region in southern Spain. SUBJECTS: The study was carried out with a random sample of 3528 subjects (1813 men, 1715 women) who were between 25 and 60 y of age. Blood samples were obtained for biochemical assays in a random subsample of 384 subjects (183 men, 201 women). INTERVENTIONS: Food consumption was assessed by 48-h recall. Vitamin B(6) was measured as alpha erythrocyte aspartate aminotransferase activation coefficient (alphaEAST); vitamin B(12) and folate concentrations were measured in plasma. RESULTS: Energy and vitamin intakes were significantly higher in men than in women. In men, intakes were below two-thirds of the RDA in 10.8, 2.9 and 22.6% for B(6), B(12) and folate, respectively. The corresponding figures in women were 16.7, 5.1 and 23.5% for vitamins B(6), B(12) and folate. Age, place of residence and educational level, alcohol use and smoking were also associated with differences in the intake of these nutrients. Biochemical analyses showed that vitamins B(6), B(12) and folate status was acceptable in 75.7, 89.1 and 57.6% of the population, respectively. Plasma concentration of folate was significantly higher in women. CONCLUSION: Our results provide a precise estimate of the nutritional status for vitamins B(6), B(12) and folate in the adult population of southern Spain. Factors such as age, place of residence, level of education and smoking can increase the risk of inadequate intake of some nutrients. However, these factors did not affect biochemical indexes of nutritional status in the present study. SPONSORSHIP: Dirección General de Salud Pública and the Health Council of the Andalusian Regional Government.
OBJECTIVE: To assess the nutritional status for vitamins B(6) and B(12) and folate in an adult Mediterranean population, in order to identify patterns of intake, groups at risk for deficiency, and factors that might influence this risk. DESIGN: A cross-sectional epidemiological survey. SETTING: Andalusia, a western Mediterranean region in southern Spain. SUBJECTS: The study was carried out with a random sample of 3528 subjects (1813 men, 1715 women) who were between 25 and 60 y of age. Blood samples were obtained for biochemical assays in a random subsample of 384 subjects (183 men, 201 women). INTERVENTIONS: Food consumption was assessed by 48-h recall. Vitamin B(6) was measured as alpha erythrocyte aspartate aminotransferase activation coefficient (alphaEAST); vitamin B(12) and folate concentrations were measured in plasma. RESULTS: Energy and vitamin intakes were significantly higher in men than in women. In men, intakes were below two-thirds of the RDA in 10.8, 2.9 and 22.6% for B(6), B(12) and folate, respectively. The corresponding figures in women were 16.7, 5.1 and 23.5% for vitamins B(6), B(12) and folate. Age, place of residence and educational level, alcohol use and smoking were also associated with differences in the intake of these nutrients. Biochemical analyses showed that vitamins B(6), B(12) and folate status was acceptable in 75.7, 89.1 and 57.6% of the population, respectively. Plasma concentration of folate was significantly higher in women. CONCLUSION: Our results provide a precise estimate of the nutritional status for vitamins B(6), B(12) and folate in the adult population of southern Spain. Factors such as age, place of residence, level of education and smoking can increase the risk of inadequate intake of some nutrients. However, these factors did not affect biochemical indexes of nutritional status in the present study. SPONSORSHIP: Dirección General de Salud Pública and the Health Council of the Andalusian Regional Government.
Authors: Eric D Ciappio; Zhenhua Liu; Ryan S Brooks; Joel B Mason; Roderick T Bronson; Jimmy W Crott Journal: Gut Date: 2011-06-09 Impact factor: 23.059
Authors: Edward Yu; Christopher Papandreou; Miguel Ruiz-Canela; Marta Guasch-Ferre; Clary B Clish; Courtney Dennis; Liming Liang; Dolores Corella; Montserrat Fitó; Cristina Razquin; José Lapetra; Ramón Estruch; Emilio Ros; Montserrat Cofán; Fernando Arós; Estefania Toledo; Lluis Serra-Majem; José V Sorlí; Frank B Hu; Miguel A Martinez-Gonzalez; Jordi Salas-Salvado Journal: Clin Chem Date: 2018-06-08 Impact factor: 8.327
Authors: Zhenhua Liu; Eric D Ciappio; Jimmy W Crott; Ryan S Brooks; Jared Nesvet; Donald E Smith; Sang-Woon Choi; Joel B Mason Journal: FASEB J Date: 2011-06-06 Impact factor: 5.191
Authors: Claire M Marchetta; Owen J Devine; Krista S Crider; Becky L Tsang; Amy M Cordero; Yan Ping Qi; Jing Guo; Robert J Berry; Jorge Rosenthal; Joseph Mulinare; Patricia Mersereau; Heather C Hamner Journal: Nutrients Date: 2015-04-10 Impact factor: 5.717
Authors: Joan K Morris; Marie-Claude Addor; Elisa Ballardini; Ingeborg Barisic; Laia Barrachina-Bonet; Paula Braz; Clara Cavero-Carbonell; Elly Den Hond; Ester Garne; Miriam Gatt; Martin Haeusler; Babak Khoshnood; Nathalie Lelong; Agnieszka Kinsner-Ovaskainen; Sonja Kiuru-Kuhlefelt; Kari Klungsoyr; Anna Latos-Bielenska; Elizabeth Limb; Mary T O'Mahony; Isabelle Perthus; Anna Pierini; Judith Rankin; Anke Rissmann; Florence Rouget; Gerardine Sayers; Antonin Sipek; Sarah Stevens; David Tucker; Christine Verellen-Dumoulin; Hermien E K de Walle; Diana Wellesley; Wladimir Wertelecki; Eva Bermejo-Sanchez Journal: Front Pediatr Date: 2021-06-24 Impact factor: 3.418
Authors: Christos M Hatzis; George K Bertsias; Manolis Linardakis; John M Scott; Anthony G Kafatos Journal: Nutr J Date: 2006-02-10 Impact factor: 3.271