Literature DB >> 127915

Lipogenesis by intact hepatocytes from normal and diabetic rats.

E Raghupathy, C Orthlieb, S Abraham.   

Abstract

Intact hepatocytes isolated from livers of diabetic rats demonstrate the characteristic decreased lipogenic capacities as compared to normal. Administration of insulin to diabetic rats restores these capacities to near normal levels. The results emphasize the potential that the hepatocyte system has for the study of hormonal regulation of lipogenesis.

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Year:  1975        PMID： 127915     DOI： 10.1007/bf02532756

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  11 in total

1.  FATTY ACID SYNTHESIS BY COMPLEX SYSTEMS. THE POSSIBILITY OF REGULATION BY MICROSOMES.

Authors:  E LORCH; S ABRAHAM; I L CHAIKOFF
Journal:  Biochim Biophys Acta       Date:  1963-12-27

2.  A simple method for the isolation and purification of total lipides from animal tissues.

Authors:  J FOLCH; M LEES; G H SLOANE STANLEY
Journal:  J Biol Chem       Date:  1957-05       Impact factor: 5.157

3.  Two blocks in carbohydrate utilization in the liver of the diabetic rat.

Authors:  S S CHERNICK; I L CHAIKOFF
Journal:  J Biol Chem       Date:  1951-01       Impact factor: 5.157

4.  Lipogenesis in rat hepatocytes.

Authors:  D G Clark; R Rognstad; J Katz
Journal:  J Biol Chem       Date:  1974-04-10       Impact factor: 5.157

5.  The regulation of lipogenesis by cyclic nucleotides in intact hepatocytes prepared by a simplified technique.

Authors:  D M Capuzzi; V Rothman; S Margolis
Journal:  J Biol Chem       Date:  1974-02-25       Impact factor: 5.157

6.  Protein synthesis in single cell suspensions from rat liver. I. General properties of the system and permeability of the cells for leucine and methionine.

Authors:  G Schreiber; M Schreiber
Journal:  J Biol Chem       Date:  1972-10-10       Impact factor: 5.157

7.  The regulation of gluconeogenesis in isolated rat liver cells by glucagon, insulin, dibutyryl cyclic adenosine monophosphate, and fatty acids.

Authors:  M E Johnson; N M Das; F R Butcher; J N Fain
Journal:  J Biol Chem       Date:  1972-05-25       Impact factor: 5.157

8.  Glucose and acetate utilization by hyperplastic, alveolar nodule outgrowths and adenocarcinomas of mouse mammary gland.

Authors:  J C Bartley; H McGrath; S Abraham
Journal:  Cancer Res       Date:  1971-05       Impact factor: 12.701

9.  High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study.

Authors:  M N Berry; D S Friend
Journal:  J Cell Biol       Date:  1969-12       Impact factor: 10.539
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