Literature DB >> 12791391

Raf kinases in lung tumor development.

Ulf R Rapp1, Joachim Fensterle, Stefan Albert, Rudolf Götz.   

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Year:  2003        PMID： 12791391     DOI： 10.1016/s0065-2571(03)00002-5

Source DB:  PubMed          Journal:  Adv Enzyme Regul        ISSN： 0065-2571


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  8 in total

1.  Development of a novel class of B-Raf(V600E)-selective inhibitors through virtual screening and hierarchical hit optimization.

Authors:  Xiangqian Kong; Jie Qin; Zeng Li; Adina Vultur; Linjiang Tong; Enguang Feng; Geena Rajan; Shien Liu; Junyan Lu; Zhongjie Liang; Mingyue Zheng; Weiliang Zhu; Hualiang Jiang; Meenhard Herlyn; Hong Liu; Ronen Marmorstein; Cheng Luo
Journal:  Org Biomol Chem       Date:  2012-09-28       Impact factor: 3.876

Review 2.  Raf kinases: function, regulation and role in human cancer.

Authors:  Deborah T Leicht; Vitaly Balan; Alexander Kaplun; Vinita Singh-Gupta; Ludmila Kaplun; Melissa Dobson; Guri Tzivion
Journal:  Biochim Biophys Acta       Date:  2007-05-22

3.  MEK-1 activates C-Raf through a Ras-independent mechanism.

Authors:  Deborah T Leicht; Vitaly Balan; Jun Zhu; Alexander Kaplun; Agnieszka Bronisz; Ajay Rana; Guri Tzivion
Journal:  Biochim Biophys Acta       Date:  2013-01-27

4.  A-RAF kinase functions in ARF6 regulated endocytic membrane traffic.

Authors:  Elena Nekhoroshkova; Stefan Albert; Matthias Becker; Ulf R Rapp
Journal:  PLoS One       Date:  2009-02-27       Impact factor: 3.240

5.  Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosis.

Authors:  Roland Houben; Jürgen C Becker; Andreas Kappel; Patrick Terheyden; Eva-B Bröcker; Rudolf Goetz; Ulf R Rapp
Journal:  J Carcinog       Date:  2004-03-26

6.  Use of mitogenic cascade blockers for treatment of C-Raf induced lung adenoma in vivo: CI-1040 strongly reduces growth and improves lung structure.

Authors:  Boris W Kramer; Rudolf Götz; Ulf R Rapp
Journal:  BMC Cancer       Date:  2004-06-01       Impact factor: 4.430

7.  B-Raf specific antibody responses in melanoma patients.

Authors:  Joachim Fensterle; Jürgen C Becker; Tamara Potapenko; Veronika Heimbach; Claudia S Vetter; Eva B Bröcker; Ulf R Rapp
Journal:  BMC Cancer       Date:  2004-09-12       Impact factor: 4.430

Review 8.  Conferring specificity on the ubiquitous Raf/MEK signalling pathway.

Authors:  E O'Neill; W Kolch
Journal:  Br J Cancer       Date:  2004-01-26       Impact factor: 7.640
  8 in total

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