Literature DB >> 12790596

Synthesis, isolation, and characterization of 2'-paclitaxel glycinate: an application of the Bsmoc protecting group.

Richard B Greenwald1, Hong Zhao, Prasanna Reddy.   

Abstract

The relevance of the Bsmoc protecting group in the synthesis of moisture- and base-sensitive compounds has been demonstrated by the preparation of 2'-paclitaxel glycinate with use of the solid anhydrous base, 4-piperidinopiperidine in DCM solvent.

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Year:  2003        PMID： 12790596     DOI： 10.1021/jo034077s

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

1.  [DLys(6)]-luteinizing hormone releasing hormone-curcumin conjugate inhibits pancreatic cancer cell growth in vitro and in vivo.

Authors:  S Aggarwal; M W Ndinguri; R Solipuram; N Wakamatsu; R P Hammer; D Ingram; W Hansel
Journal:  Int J Cancer       Date:  2011-07-20       Impact factor: 7.396

2.  1,1-dioxonaphtho[1,2-b]thiophene-2-methyloxycarbonyl (alpha-Nsmoc) and 3,3-dioxonaphtho[2,1-b]thiophene-2-methyloxycarbonyl (beta-Nsmoc) amino-protecting groups.

Authors:  Louis A Carpino; Adel Ali Abdel-Maksoud; Dumitru Ionescu; E M E Mansour; Mohamed A Zewail
Journal:  J Org Chem       Date:  2007-02-08       Impact factor: 4.354

3.  Heparin-paclitaxel conjugates using mixed anhydride as intermediate: synthesis, influence of polymer structure on drug release, anticoagulant activity and in vitro efficiency.

Authors:  Ying Wang; Dingcheng Xin; Kaijian Liu; Jiannan Xiang
Journal:  Pharm Res       Date:  2008-11-18       Impact factor: 4.200
  3 in total

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