Literature DB >> 12790546

Microwave-assisted C-H bond activation: a rapid entry into functionalized heterocycles.

Kian L Tan1, Anil Vasudevan, Robert G Bergman, Jonathan A Ellman, Andrew J Souers.   

Abstract

[reaction: see text] Microwave irradiation strongly accelerates the rhodium-catalyzed intramolecular coupling of a benzimidazole C-H bond to pendant alkenes. The cyclic products were formed in moderate to excellent yields with reaction times less than 20 min. Additionally, the use of microwave irradiation allowed the reactions to be performed without any solvent purification and with minimal precautions to exclude air.

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Year:  2003        PMID： 12790546     DOI： 10.1021/ol030050j

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  6 in total

Review 1.  Direct transition metal-catalyzed functionalization of heteroaromatic compounds.

Authors:  Ilya V Seregin; Vladimir Gevorgyan
Journal:  Chem Soc Rev       Date:  2007-03-05       Impact factor: 54.564

2.  One pot three component reaction for the rapid synthesis of pyrrolo[1,2-a]benzimidazoles.

Authors:  Wei-Shun Hsu; Vijaykumar Paike; Chung-Ming Sun
Journal:  Mol Divers       Date:  2013-03-26       Impact factor: 2.943

Review 3.  Direct functionalization of nitrogen heterocycles via Rh-catalyzed C-H bond activation.

Authors:  Jared C Lewis; Robert G Bergman; Jonathan A Ellman
Journal:  Acc Chem Res       Date:  2008-07-11       Impact factor: 22.384

Review 4.  Rhodium-catalyzed C-C bond formation via heteroatom-directed C-H bond activation.

Authors:  Denise A Colby; Robert G Bergman; Jonathan A Ellman
Journal:  Chem Rev       Date:  2010-02-10       Impact factor: 60.622

5.  Experimental and computational studies on the mechanism of N-heterocycle C-H activation by Rh(I).

Authors:  Sean H Wiedemann; Jared C Lewis; Jonathan A Ellman; Robert G Bergman
Journal:  J Am Chem Soc       Date:  2006-02-22       Impact factor: 15.419

Review 6.  Advances in the Synthesis of Ring-Fused Benzimidazoles and Imidazobenzimidazoles.

Authors:  Martin Sweeney; Darren Conboy; Styliana I Mirallai; Fawaz Aldabbagh
Journal:  Molecules       Date:  2021-05-04       Impact factor: 4.411
  6 in total

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