Literature DB >> 12789623

LY-354740 (Eli Lilly).

Andrzej Pilc1.   

Abstract

Lilly is developing LY-354740, the lead compound in a series of derivatives of the metabotropic glutamate receptor group II agonist L-CCG-1, for the potential treatment of anxiety [212536], [276941], [276942].

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Year:  2003        PMID： 12789623

Source DB:  PubMed          Journal:  IDrugs        ISSN： 1369-7056


  6 in total

1.  Radiosynthesis of PET radiotracer as a prodrug for imaging group II metabotropic glutamate receptors in vivo.

Authors:  Ji-Quan Wang; Zhaoda Zhang; Darshini Kuruppu; Anna-Liisa Brownell
Journal:  Bioorg Med Chem Lett       Date:  2012-01-21       Impact factor: 2.823

2.  Effects of the mGluR2/3 agonist LY354740 on computerized tasks of attention and working memory in marmoset monkeys.

Authors:  Simona Spinelli; Theresa Ballard; Silvia Gatti-McArthur; Grayson J Richards; Martin Kapps; Thomas Woltering; Jurgen Wichmann; Heinz Stadler; Joram Feldon; Christopher R Pryce
Journal:  Psychopharmacology (Berl)       Date:  2005-01-28       Impact factor: 4.530

3.  Identification of Metabotropic Glutamate Receptor Subtype 5 Potentiators Using Virtual High-Throughput Screening.

Authors:  Ralf Mueller; Alice L Rodriguez; Eric S Dawson; Mariusz Butkiewicz; Thuy T Nguyen; Stephen Oleszkiewicz; Annalen Bleckmann; C David Weaver; Craig W Lindsley; P Jeffrey Conn; Jens Meiler
Journal:  ACS Chem Neurosci       Date:  2010-01-28       Impact factor: 4.418

4.  Allosteric potentiators of metabotropic glutamate receptor subtype 1a differentially modulate independent signaling pathways in baby hamster kidney cells.

Authors:  Douglas J Sheffler; P Jeffrey Conn
Journal:  Neuropharmacology       Date:  2008-07-02       Impact factor: 5.250

Review 5.  Novel pharmacological treatments for generalized anxiety disorder: Pediatric considerations.

Authors:  A Irem Sonmez; Ammar Almorsy; Laura B Ramsey; Jeffrey R Strawn; Paul E Croarkin
Journal:  Depress Anxiety       Date:  2020-05-17       Impact factor: 6.505

6.  Investigation on quantitative structure activity relationships and pharmacophore modeling of a series of mGluR2 antagonists.

Authors:  Meng-Qi Zhang; Xiao-Le Zhang; Yan Li; Wen-Jia Fan; Yong-Hua Wang; Ming Hao; Shu-Wei Zhang; Chun-Zhi Ai
Journal:  Int J Mol Sci       Date:  2011-09-16       Impact factor: 5.923
  6 in total

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