| Literature DB >> 12788366 |
Thomas Rühl1, Mohammed Daghish, Andrij Buchynskyy, Karen Barche, Daniela Volke, Katherina Stembera, Uwe Kempin, Dietmar Knoll, Lothar Hennig, Matthias Findeisen, Ramona Oehme, Sabine Giesa, Juan Ayala, Peter Welzel.
Abstract
The interaction of a moenomycin derivative with the enzyme penicillin binding protein 1b (PBP 1b) has been studied by means of STD NMR. The results obtained initiated the synthesis of a number of moenomycin derivatives modified in unit A including a moenomycin-ampicillin conjugate and determination of their antibiotic activities. A protocol is described that allows studying the interaction of moenomycin analogues with PBP 1b by fluorescence correlation spectroscopy.Entities:
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Year: 2003 PMID： 12788366 DOI： 10.1016/s0968-0896(03)00187-1
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641