PURPOSE: To report childhood infection with Baylisascaris procyonis (raccoon round worm) manifesting as diffuse unilateral subacute neuroretinitis (DUSN) and choroidal infiltrates in association with neurologic disease (neural larva migrans). METHOD: Observational case series, one with eye manifestations of DUSN, the other with choroidal infiltrates, both with severe neurologic degeneration. RESULTS: Indirect immunofluorescence assays on serum and cerebrospinal fluid were positive for B. procyonis in one and serially positive and increasing in the other. Both children had a history of pica and raccoon exposure. CONCLUSIONS: Baylisascaris procyonis infection is associated with two cases of severe neurologic degeneration with ocular lesions: DUSN and choroidal infiltrates. Although B. procyonis is known to cause DUSN, these cases indicate that concomitant ocular migration may accompany neural larva migrans. These are the third and forth cases in the US literature of neural larva migrans due to B. procyonis with eye findings.
PURPOSE: To report childhood infection with Baylisascaris procyonis (raccoon round worm) manifesting as diffuse unilateral subacute neuroretinitis (DUSN) and choroidal infiltrates in association with neurologic disease (neural larva migrans). METHOD: Observational case series, one with eye manifestations of DUSN, the other with choroidal infiltrates, both with severe neurologic degeneration. RESULTS: Indirect immunofluorescence assays on serum and cerebrospinal fluid were positive for B. procyonis in one and serially positive and increasing in the other. Both children had a history of pica and raccoon exposure. CONCLUSIONS:Baylisascaris procyonis infection is associated with two cases of severe neurologic degeneration with ocular lesions: DUSN and choroidal infiltrates. Although B. procyonis is known to cause DUSN, these cases indicate that concomitant ocular migration may accompany neural larva migrans. These are the third and forth cases in the US literature of neural larva migrans due to B. procyonis with eye findings.
Authors: Jason E Perlman; Kevin R Kazacos; Gavin H Imperato; Rajen U Desai; Susan K Schulman; Jon Edwards; Lucy R Pontrelli; Fabiana S Machado; Herbert B Tanowitz; Norman A Saffra Journal: J Neuroparasitology Date: 2010
Authors: Jan Hajek; Yvonne Yau; Peter Kertes; Teesta Soman; Suzanne Laughlin; Ronik Kanani; Kevin Kazacos; Sriveny Dangoudoubiyam; Mary Anne Opavsky Journal: Can J Infect Dis Med Microbiol Date: 2009 Impact factor: 2.471
Authors: Norman A Saffra; Jason E Perlman; Rajen U Desai; Kevin R Kazacos; Christina M Coyle; Fabiana S Machado; Sanjay R Kedhar; Michael Engelbert; Herbert B Tanowitz Journal: J Neuroparasitology Date: 2010-01-01