| Literature DB >> 12787565 |
Alexei V Tumanov1, Dmitry V Kuprash, Sergei A Nedospasov.
Abstract
Secondary lymphoid organs provide the necessary microenvironment for the cooperation of antigen-specific T- and B-lymphocytes and antigen-presenting cells in order to initiate an efficient immune response. Remarkable progress in understanding of the mechanisms of lymphoid organogenesis was achieved due to the analysis of various gene-targeted mice. This review primarily focuses on the role of lymphotoxin (LT) in development, maturation and maintenance of secondary lymphoid organs.Entities:
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Year: 2003 PMID： 12787565 DOI： 10.1016/s1359-6101(03)00026-1
Source DB: PubMed Journal: Cytokine Growth Factor Rev ISSN： 1359-6101 Impact factor: 7.638