Literature DB >> 12786713

Radical resection of giant congenital melanocytic nevus and reconstruction with meek-graft covered integra dermal template.

Jürgen Kopp1, E Magnus Noah, Albert Rübben, Hans F Merk, Norbert Pallua.   

Abstract

BACKGROUND: Giant congenital melanocytic nevi represent a surgical challenge, particularly in cases in which the size of the nevus exceeds certain extend and malignant transformations have to be considered.
OBJECTIVE: To discuss through case report considerable surgical options when extensive giant congenital melanocytic nevi with malignant transformation are encountered.
METHODS: We present an unusual case of a giant congenital melanocytic nevi of the entire back of a 44-year-old patient. To achieve radical resection with direct appropriate wound closure and acceptable outcome, the integument of the entire back was excised and covered with Integra, followed by split-thickness skin grafting after stable integration of the matrix.
RESULTS: The approach resulted in a complete excision of the tumor and acceptable cosmetic and excellent biomechanical outcome.
CONCLUSION: The introduced practice demonstrates a useful alternative to established methods, particularly if tumor excision in large areas and subsequent wound closure might be achieved in one procedure.

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Year:  2003        PMID: 12786713     DOI: 10.1046/j.1524-4725.2003.29157.x

Source DB:  PubMed          Journal:  Dermatol Surg        ISSN: 1076-0512            Impact factor:   3.398


  5 in total

Review 1.  The micrograft concept for wound healing: strategies and applications.

Authors:  Atanu Biswas; Manish Bharara; Craig Hurst; David G Armstrong; Horacio Rilo
Journal:  J Diabetes Sci Technol       Date:  2010-07-01

Review 2.  New technologies in global burn care - a review of recent advances.

Authors:  Laura Kearney; Eamon C Francis; Anthony Jp Clover
Journal:  Int J Burns Trauma       Date:  2018-08-20

Review 3.  Use of Integra for Reconstruction after Nevi Resection: A Systematic Review and Pooled Analysis of Reported Cases.

Authors:  Jude Opoku-Agyeman; Kayla Humenansky; Wellington Davis; Paul Glat
Journal:  Surg Res Pract       Date:  2019-10-09

Review 4.  Skin tissue engineering advances in severe burns: review and therapeutic applications.

Authors:  Alvin Wen Choong Chua; Yik Cheong Khoo; Bien Keem Tan; Kok Chai Tan; Chee Liam Foo; Si Jack Chong
Journal:  Burns Trauma       Date:  2016-02-19

Review 5.  Tissue engineering of skin and regenerative medicine for wound care.

Authors:  Steven T Boyce; Andrea L Lalley
Journal:  Burns Trauma       Date:  2018-01-24
  5 in total

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