Literature DB >> 12784068

Complications of intrathecal baclofen pumps in children.

Judith L Gooch1, Wende A Oberg, Barbara Grams, Lorrie A Ward, Marion L Walker.   

Abstract

Intrathecal baclofen is increasingly being used to manage severe spasticity in children. Although substantial tone reduction with this treatment has been documented, complications also occur. In this study, we describe the device- and major non-device-related complications in a group of 100 consecutive children and young adults who received 117 intrathecal baclofen pumps for the management of severe spasticity. Twenty-four patients (24%) experienced a total of 48 complications. The most common complication was disconnection of the catheter at its connection to the pump, occurring in 9% of pumps implanted. This complication occurred more frequently in pumps with catheter access ports (16%) than in those without ports (2%). Catheter dislodgement from the intrathecal space was the next most common complication, occurring in 8% of pumps implanted (13% of pumps with ports, 4% of pumps without ports). To decrease the occurrence of the most common complications of intrathecal pumps, we now typically implant pumps without catheter access ports, and we use 2-piece catheters. Although the lack of an access port may be a disadvantage for troubleshooting, most complications can be detected in pumps without a port. Patient and family education is critical in preventing serious consequences of baclofen withdrawal resulting from catheter-related complications. Copyright 2003 S. Karger AG, Basel

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Year:  2003        PMID: 12784068     DOI: 10.1159/000070870

Source DB:  PubMed          Journal:  Pediatr Neurosurg        ISSN: 1016-2291            Impact factor:   1.162


  12 in total

Review 1.  Imaging evaluation of intrathecal baclofen pump-catheter systems.

Authors:  A C Miracle; M A Fox; R N Ayyangar; A Vyas; S K Mukherji; D J Quint
Journal:  AJNR Am J Neuroradiol       Date:  2010-10-28       Impact factor: 3.825

Review 2.  Intrathecal baclofen for childhood hypertonia.

Authors:  A Leland Albright
Journal:  Childs Nerv Syst       Date:  2007-06-29       Impact factor: 1.475

3.  The use of opioids in children receiving intrathecal baclofen therapy.

Authors:  Giuliana Rizzo; Leonardo Bussolin; Lorenzo Genitori; Anna Zicca; Andrea Messeri; Matteo Lenge; Flavio Giordano
Journal:  Childs Nerv Syst       Date:  2019-04-26       Impact factor: 1.475

4.  Placement of baclofen pumps through the foramen magnum and upper cervical spine.

Authors:  Kristine Dziurzynski; Deborah Mcleish; Michael Ward; Bermans J Iskandar
Journal:  Childs Nerv Syst       Date:  2005-06-11       Impact factor: 1.475

5.  Intrathecal baclofen therapy: complication avoidance and management.

Authors:  Neil Haranhalli; Dhanya Anand; Jeffrey H Wisoff; David H Harter; Howard L Weiner; Michelle Blate; Jonathan Roth
Journal:  Childs Nerv Syst       Date:  2010-09-18       Impact factor: 1.475

6.  Status dystonicus resembling the intrathecal baclofen withdrawal syndrome: a case report and review of the literature.

Authors:  William Muirhead; Ibrahim Jalloh; Michael Vloeberghs
Journal:  J Med Case Rep       Date:  2010-08-31

7.  Intrathecal baclofen pump for spasticity: an evidence-based analysis.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2005-05-01

8.  Evaluation of usefulness of scintigraphic imaging in diagnosis of intrathecal drug delivery system malfunction - a preliminary report.

Authors:  Jacek Teodorczyk; Tomasz Szmuda; Mariusz Siemiński; Piotr Lass; Paweł Słoniewski
Journal:  Pol J Radiol       Date:  2013-07

9.  CNS penetration of intrathecal-lumbar idursulfase in the monkey, dog and mouse: implications for neurological outcomes of lysosomal storage disorder.

Authors:  Pericles Calias; Mikhail Papisov; Jing Pan; Nancy Savioli; Vasily Belov; Yan Huang; Jason Lotterhand; Mary Alessandrini; Nan Liu; Alan J Fischman; Jan L Powell; Michael W Heartlein
Journal:  PLoS One       Date:  2012-01-18       Impact factor: 3.240

10.  Interaction of ventriculoperitoneal shunt and baclofen pump.

Authors:  Daniel H Fulkerson; Joel C Boaz; Thomas G Luerssen
Journal:  Childs Nerv Syst       Date:  2007-03-16       Impact factor: 1.532

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