Literature DB >> 1278327

Precocious puberty in rats induced by hypothalamic lesions: a comparison of platinum and stainless steel electrodes.

K B Ruf, E V YoungLai, J H Kitchen, M Vuillet.   

Abstract

Precocious sexual maturation was induced in immature female rats by 2 types of unilateral hypothalamic lesions. Stainless steel electrodes produced smaller tissue defects but proved more efficient than platinum electrodes.

Entities:  

Keywords:  Animals, Laboratory; Biology; Central Nervous System; Clinical Research; Comparative Studies; Examinations And Diagnoses; Genitalia; Genitalia, Female; Hypothalamus; Ingredients And Chemicals; Inorganic Chemicals; Laboratory Examinations And Diagnoses; Laboratory Procedures; Metals; Ovarian Effects; Ovary; Ovulation; Physiology; Platinum--side effects; Reproduction; Research Methodology; Stainless Steel--side effects; Studies; Urogenital System

Mesh:

Substances:

Year:  1976        PMID: 1278327     DOI: 10.1007/BF01990222

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  12 in total

1.  Brain lesions and precocious puberty in rats.

Authors:  K B Ruf; M Wilkinson; D De Ziegler
Journal:  Nature       Date:  1975-10-02       Impact factor: 49.962

2.  The hypothalamus and sexual maturation in the rat.

Authors:  B T DONOVAN; J J VAN DER WERFF TEN BOSCH
Journal:  J Physiol       Date:  1959-06-23       Impact factor: 5.182

3.  Irritative deposits from stainless steel electrodes in the preoptic rat brain causing release of pituitary gonadotropin.

Authors:  J W EVERETT; H M RADFORD
Journal:  Proc Soc Exp Biol Med       Date:  1961-12

4.  Immunohistochemical localization of luteinizing hormone-releasing hormone in the rat median eminence.

Authors:  G Pelletier; F Labrie; R Puviani; A Arimura; A V Schally
Journal:  Endocrinology       Date:  1974-07       Impact factor: 4.736

5.  Induction of precocious sexual maturation in female rats by electrochemical stimulation of the brain.

Authors:  K B Ruf; E V Younglai; M J Holmes
Journal:  Brain Res       Date:  1974-10-04       Impact factor: 3.252

6.  Opposite effects of platinum and stainless-steel lesions of the amygdala on gonadotropin secretion.

Authors:  M E Velasco
Journal:  Neuroendocrinology       Date:  1972       Impact factor: 4.914

7.  Steroid secretion and the aromatization of androgens by rabbit thecal cells.

Authors:  E V Younglai
Journal:  Endocrinology       Date:  1972-11       Impact factor: 4.736

8.  Differential effects of anterior and middle hypothalamic lesions on vaginal opening and cyclicity.

Authors:  H M Meijs-Roelofs; J Moll
Journal:  Neuroendocrinology       Date:  1972       Impact factor: 4.914

9.  Localization of luteinizing hormone-releasing hormone in the preoptic area and hypothalamus of the rat using radioimmunoassay.

Authors:  J E Wheaton; L Krulich; S M McCann
Journal:  Endocrinology       Date:  1975-07       Impact factor: 4.736

10.  Luteinizing hormone-releasing hormone (LH-RH) content of the hypothalamic nuclei in rat.

Authors:  M Palkovits; A Arimura; M Brownstein; A V Schally; J M Saavedra
Journal:  Endocrinology       Date:  1974-08       Impact factor: 4.736

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