Literature DB >> 1278308

Ultrastructural changes in the dorsal root ganglia evoked by thalidomide in rabbits.

P A Stokes, W J Lykke, W G McBride.   

Abstract

Administration of the teratogenic drug thalidomide to pregnant does produces ultrastructural changes in foetal ganglion cells, Schwann cells and axons in the posterior root ganglia corresponding to forelimb segments deformed by the orug. Ultrastructural changes in ganglia appear on the 13th day of gestation, i.e., preceding the appearance of limb malformation.

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Year:  1976        PMID: 1278308     DOI: 10.1007/BF01990184

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  1 in total

1.  Fetal nerve cell degeneration produced by thalidomide in rabbits.

Authors:  W G McBride
Journal:  Teratology       Date:  1974-12
  1 in total
  1 in total

Review 1.  Environmental teratogens.

Authors:  R L Brent; D A Beckman
Journal:  Bull N Y Acad Med       Date:  1990 Mar-Apr
  1 in total

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