Literature DB >> 12781803

Cytotoxic pentacyclic triterpenes from Combretum nigricans.

G Simon1, J Dewelle, O Nacoulma, P Guissou, R Kiss, D Daloze, J C Braekman.   

Abstract

A new pentacyclic triterpene, 11alpha-acetoxy-20,24-epoxy-25-hydroxy-dammar-3-one (1), has been isolated from the African tree Combretum nigricans, together with the known corresponding diol, 20,24-epoxy-11alpha, 25-dihydroxy-dammar-3-one (2). They are responsible, at least in part, for the cytotoxic activity of the methanolic extract of the plant.

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Year:  2003        PMID: 12781803     DOI: 10.1016/s0367-326x(03)00046-7

Source DB:  PubMed          Journal:  Fitoterapia        ISSN: 0367-326X            Impact factor:   2.882


  2 in total

Review 1.  Bioactivities of the genus Combretum (Combretaceae): a review.

Authors:  Gedson Rodrigues de Morais Lima; Igor Rafael Praxedes de Sales; Marcelo Ricardo Dutra Caldas Filho; Neyres Zínia Taveira de Jesus; Heloina de Sousa Falcão; José Maria Barbosa-Filho; Analúcia Guedes Silveira Cabral; Augusto Lopes Souto; Josean Fechine Tavares; Leônia Maria Batista
Journal:  Molecules       Date:  2012-08-02       Impact factor: 4.411

2.  Bioactive pentacyclic triterpenes from the stems of Combretum laxum.

Authors:  Eder Bisoli; Walmir Silva Garcez; Lidilhone Hamerski; Caroline Tieppo; Fernanda Rodrigues Garcez
Journal:  Molecules       Date:  2008-11-01       Impact factor: 4.411

  2 in total

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