| Literature DB >> 12781358 |
Olufunmilayo I Olopade1, Minjie Wei.
Abstract
A new model of ovarian cancer tumor progression implicates aberrant FANCF promoter methylation that is associated with gene silencing and disruption of the Fanconi-anemia-BRCA pathway. Disruption of the pathway occurs de novo in ovarian cancers and may contribute to selective sensitivity to platinum salts.Entities:
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Year: 2003 PMID: 12781358 DOI: 10.1016/s1535-6108(03)00111-9
Source DB: PubMed Journal: Cancer Cell ISSN: 1535-6108 Impact factor: 31.743