| Literature DB >> 12781200 |
Zheng Yan1, Michael Kahn, Maher Qabar, Jan Urban, Hwa-Ok Kim, Mark A Blaskovich.
Abstract
Selective inhibitors of protein tyrosine phosphatases (PTPases) are of great interest as therapeutic agents and research tools. Several phenylalanine derivatives (1, 2) designed as phosphotyrosine mimetics or irreversible active site inhibitors were successfully synthesized, then incorporated into a combinatorial library based on a peptidomimetic beta-strand template.Entities:
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Year: 2003 PMID： 12781200 DOI： 10.1016/s0960-894x(03)00253-1
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823