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Literature DB >> 12781153

Telomere replication: an Est fest.

Abstract

The search for subunits of the telomerase enzyme has uncovered orthologs of the budding years Est1 protein in several species, including humans. Thus, positive regulation of telomerase by Est1 appears to be a widely utilized mechanism for maintaining telomere length homeostasis.

Entities: Gene Species

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Year: 2003 PMID： 12781153 DOI： 10.1016/s0960-9822(03)00365-8

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

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Cited

14 in total

1. A genome-wide telomere screen in yeast: the long and short of it all.

Authors: Dawn Edmonds; Bobby-Joe Breitkreutz; Lea Harrington
Journal: Proc Natl Acad Sci U S A Date: 2004-06-22 Impact factor: 11.205

Review 2. Plasticity of telomere maintenance mechanisms in yeast.

Authors: Neal F Lue
Journal: Trends Biochem Sci Date: 2009-10-19 Impact factor: 13.807

3. Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain.

Authors: Elaine J Middleman; Jinkuk Choi; Andrew S Venteicher; Peggie Cheung; Steven E Artandi
Journal: Mol Cell Biol Date: 2006-03 Impact factor: 4.272

4. Telomerase regulatory subunit Est3 in two Candida species physically interacts with the TEN domain of TERT and telomeric DNA.

Authors: Wei-Feng Yen; Lidia Chico; Ming Lei; Neal F Lue
Journal: Proc Natl Acad Sci U S A Date: 2011-06-17 Impact factor: 11.205

5. Structural elements required for association of the Saccharomyces cerevisiae telomerase RNA with the Est2 reverse transcriptase.

Authors: Andrew S Chappell; Victoria Lundblad
Journal: Mol Cell Biol Date: 2004-09 Impact factor: 4.272

Telomere replication: an Est fest.

1. A genome-wide telomere screen in yeast: the long and short of it all.

Review 2. Plasticity of telomere maintenance mechanisms in yeast.

3. Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain.

4. Telomerase regulatory subunit Est3 in two Candida species physically interacts with the TEN domain of TERT and telomeric DNA.

5. Structural elements required for association of the Saccharomyces cerevisiae telomerase RNA with the Est2 reverse transcriptase.

6. Holoenzyme proteins required for the physiological assembly and activity of telomerase.

7. Yeast telomerase RNA: a flexible scaffold for protein subunits.

8. POT1-independent single-strand telomeric DNA binding activities in Brassicaceae.

9. Humanized telomeres and an attempt to express a functional human telomerase in yeast.

Review 10. Physiological assembly and activity of human telomerase complexes.