Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The role of p53 in the immunobiology of cutaneous squamous cell carcinoma.

Literature DB >> 12780682

The role of p53 in the immunobiology of cutaneous squamous cell carcinoma.

Abstract

Cutaneous squamous cell carcinoma is typically characterized by the over-expression of the tumour suppressor protein p53. Considerable evidence suggests that immune competence is important in the control of cutaneous SCC. We discuss the immunobiology of p53 and its relevance to cutaneous SCC, including the potential interaction with human papillomavirus.

Entities: Chemical

Mesh：

Substances：

Year: 2003 PMID： 12780682 PMCID： PMC1808735 DOI： 10.1046/j.1365-2249.2003.02159.x

Source DB: PubMed Journal: Clin Exp Immunol ISSN： 0009-9104 Impact factor: 4.330

85 in total

1. The promoter of a novel human papillomavirus (HPV77) associated with skin cancer displays UV responsiveness, which is mediated through a consensus p53 binding sequence.

Authors: K J Purdie; J Pennington; C M Proby; S Khalaf; E M de Villiers; I M Leigh; A Storey
Journal: EMBO J Date: 1999-10-01 Impact factor: 11.598

2. The ubiquity and impressive genomic diversity of human skin papillomaviruses suggest a commensalic nature of these viruses.

Authors: A Antonsson; O Forslund; H Ekberg; G Sterner; B G Hansson
Journal: J Virol Date: 2000-12 Impact factor: 5.103

3. Frequency and spectrum of HPV types detected in cutaneous squamous-cell carcinomas depend on the HPV detection system: a comparison of four PCR assays.

Authors: T Meyer; R Arndt; E Christophers; E Stockfleth
Journal: Dermatology Date: 2000 Impact factor: 5.366

4. Dendritic cells transduced with full-length wild-type p53 generate antitumor cytotoxic T lymphocytes from peripheral blood of cancer patients.

Authors: E Y Nikitina; J I Clark; J Van Beynen; S Chada; A K Virmani; D P Carbone; D I Gabrilovich
Journal: Clin Cancer Res Date: 2001-01 Impact factor: 12.531

5. Dendritic cells transduced with wild-type p53 gene elicit potent anti-tumour immune responses.

Authors: T Ishida; S Chada; M Stipanov; S Nadaf; F I Ciernik; D I Gabrilovich; D P Carbone
Journal: Clin Exp Immunol Date: 1999-08 Impact factor: 4.330

6. Characterization of CD8+ cytotoxic T lymphocyte/tumor cell interactions reflecting recognition of an endogenously expressed murine wild-type p53 determinant.

Authors: M Hilburger Ryan; S I Abrams
Journal: Cancer Immunol Immunother Date: 2001-01 Impact factor: 6.968

7. Degenerate and nested PCR: a highly sensitive and specific method for detection of human papillomavirus infection in cutaneous warts.

Authors: C A Harwood; P J Spink; T Surentheran; I M Leigh; E M de Villiers; J M McGregor; C M Proby; J Breuer
Journal: J Clin Microbiol Date: 1999-11 Impact factor: 5.948

8. Evaluation of combined vaccinia virus-mediated antitumor gene therapy with p53, IL-2, and IL-12 in a glioma model.

Authors: B Chen; T M Timiryasova; M L Andres; E H Kajioka; R Dutta-Roy; D S Gridley; I Fodor
Journal: Cancer Gene Ther Date: 2000-11 Impact factor: 5.987

9. Safety and immunogenicity of ALVAC wild-type human p53 (vCP207) by the intravenous route in rhesus macaques.

Authors: B Rosenwirth; E M Kuhn; J L Heeney; C Hurpin; J Tartaglia; M C Bonnet; P Moingeon; L Erdile
Journal: Vaccine Date: 2001-02-08 Impact factor: 3.641

10. Long lasting p53-specific T cell memory responses in the absence of anti-p53 antibodies in patients with resected primary colorectal cancer.

Authors: S H van der Burg; K de Cock; A G Menon; K L Franken; M Palmen; A Redeker; J Drijfhout; P J Kuppen; C van de Velde; L Erdile; R A Tollenaar; C J Melief; R Offringa
Journal: Eur J Immunol Date: 2001-01 Impact factor: 5.532

7 in total

1. The Immunogenetics of Non-melanoma Skin Cancer.

Authors: Sabha Mushtaq
Journal: Adv Exp Med Biol Date: 2022 Impact factor: 2.622

Review 2. Plasticity of differentiated cells in wound repair and tumorigenesis, part II: skin and intestine.

Authors: Joseph Burclaff; Jason C Mills
Journal: Dis Model Mech Date: 2018-08-31 Impact factor: 5.758

3. Transcriptomic analysis identifies differences in gene expression in actinic keratoses after treatment with imiquimod and between responders and non responders.

Authors: Megan H Trager; Emanuelle Rizk; Sharon Rose; Kuixi Zhu; Rui Chang; Larisa J Geskin; Yvonne M Saenger; Gary Goldenberg; Branden Lau; Benjamin T Fullerton; Jaya Pradhan; Michael Moore; Ayush C Srivastava; Giselle Singer; Robyn Gartrell
Journal: Sci Rep Date: 2021-04-22 Impact factor: 4.379