| Literature DB >> 12779969 |
Alejandro D. Rey1, Michael C. Mackey.
Abstract
Here cell population dynamics in which there is simultaneous proliferation and maturation is considered. The resulting mathematical model is a nonlinear first-order partial differential equation for the cell density u(t,x) in which there is retardation in both temporal (t) and maturation variables (x), and contains three parameters. The solution behavior depends on the initial function varphi(x) and a three component parameter vector P=(delta,lambda,r). For strictly positive initial functions, varphi(0) greater, similar 0, there are three homogeneous solutions of biological (i.e., non-negative) importance: a trivial solution u(t) identical with 0, a positive stationary solution u(st), and a time periodic solution u(p)(t). For varphi(0)=0 there are a number of different solution types depending on P: the trivial solution u(t), a spatially inhomogeneous stationary solution u(nh)(x), a spatially homogeneous singular solution u(s), a traveling wave solution u(tw)(t,x), slow traveling waves u(stw)(t,x), and slow traveling chaotic waves u(scw)(t,x). The regions of parameter space in which these solutions exist and are locally stable are delineated and studied.Entities:
Year: 1992 PMID: 12779969 DOI: 10.1063/1.165909
Source DB: PubMed Journal: Chaos ISSN: 1054-1500 Impact factor: 3.642