Literature DB >> 12777159

Giardiasis: pathophysiology and management.

Jason Hawrelak1.   

Abstract

Giardia, a common human parasite, can cause significant morbidity; however, natural medicine has great potential to influence the course of Giardia infection. The most beneficial way to treat giardiasis naturally may be through a combination approach, utilizing both nutritional interventions and phytotherapeutic agents. Nutritional intervention aims to reduce the acute symptoms of Giardia and help clear the infection. This can best be achieved by consuming a whole-food based, high-fiber, diet that is low in fat, lactose, and refined sugars. Additionally, ingestion of probiotics and wheat germ assists in parasite clearance. Numerous medicinal herbs show promise in the treatment of giardiasis. Berberine-containing herbs, garlic, and the Ayurvedic formulation Pippali rasayana currently have the most clinical evidence supporting their use. Blending the nutritional interventions and phytotherapeutic agents outlined in this article can minimize Giardia symptomatology and aid clearance of the parasite, without significant ill effects. As such, this therapeutic strategy should be considered the first-line approach. Antibiotic use may best be reserved for cases that fail to respond to initial treatment with natural measures.

Entities:  

Mesh:

Year:  2003        PMID: 12777159

Source DB:  PubMed          Journal:  Altern Med Rev        ISSN: 1089-5159


  16 in total

Review 1.  Plant-based Rasayana drugs from Ayurveda.

Authors:  Subramani Paranthaman Balasubramani; Padma Venkatasubramanian; Subrahmanya Kumar Kukkupuni; Bhushan Patwardhan
Journal:  Chin J Integr Med       Date:  2011-03-09       Impact factor: 1.978

2.  Giardia lamblia infection after pancreas-kidney transplantation.

Authors:  Ann Abkjaer Kristensen; Rune Horneland; Henrik Birn; My Svensson
Journal:  BMJ Case Rep       Date:  2016-01-18

3.  Deep glance on the antiparasitic anticancer activities of wheat germ oil in chronically infected immunosuppressed mice with cryptosporidiosis.

Authors:  Hagar F Abdelmaksoud; Tarek S Aboushousha; Ayman M El-Ashkar
Journal:  J Parasit Dis       Date:  2022-06-02

4.  The principal conductance in Giardia lamblia trophozoites possesses functional properties similar to the mammalian ClC-2 current.

Authors:  Eloy G Moreno-Galindo; Julio C Rodríguez-Elías; Mario A Ramírez-Herrera; José A Sánchez-Chapula; Ricardo A Navarro-Polanco
Journal:  Pflugers Arch       Date:  2013-09-17       Impact factor: 3.657

5.  Probiotics for the control of parasites: an overview.

Authors:  Marie-Agnès Travers; Isabelle Florent; Linda Kohl; Philippe Grellier
Journal:  J Parasitol Res       Date:  2011-09-28

6.  Effect of enteric parasitic infection on serum trace elements and nutritional status in upper Egyptian children.

Authors:  Doaa A Yones; Lamia A Galal; Alameldin M Abdallah; Khaled S Zaghlol
Journal:  Trop Parasitol       Date:  2015 Jan-Jun

Review 7.  Research and progress on ClC‑2 (Review).

Authors:  Hongwei Wang; Minghui Xu; Qingjie Kong; Peng Sun; Fengyun Yan; Wenying Tian; Xin Wang
Journal:  Mol Med Rep       Date:  2017-05-18       Impact factor: 2.952

8.  Giardia co-infection promotes the secretion of antimicrobial peptides beta-defensin 2 and trefoil factor 3 and attenuates attaching and effacing bacteria-induced intestinal disease.

Authors:  Anna Manko; Jean-Paul Motta; James A Cotton; Troy Feener; Ayodele Oyeyemi; Bruce A Vallance; John L Wallace; Andre G Buret
Journal:  PLoS One       Date:  2017-06-16       Impact factor: 3.240

9.  Berberine and itraconazole are not synergistic in vitro against Aspergillus fumigatus isolated from clinical patients.

Authors:  Gao Lei; He Dan; Liu Jinhua; Yan Wei; Gao Song; Wang Li
Journal:  Molecules       Date:  2011-11-03       Impact factor: 4.411

Review 10.  Probiotics in the management of Giardia duodenalis: an update on potential mechanisms and outcomes.

Authors:  Nasrin Dashti; Mitra Zarebavani
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2021-07-29       Impact factor: 3.000

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