Literature DB >> 12776036

Morbidity and mortality after self-expandable metallic stent placement in patients with progressive or recurrent esophageal cancer after chemoradiotherapy.

Tetsuya Sumiyoshi1, Takuji Gotoda, Kei Muro, Bjorn Rembacken, Masahiro Goto, Yoko Sumiyoshi, Hiroyuki Ono, Daizo Saito.   

Abstract

BACKGROUND: Placemet of self-expandable metallic stents in patients with advance esophageal cancer improves dysphagia and occludes tracheoesophageal fistulas. However, the safety of self-expandable metallic stents for patients who have undergone chemoradiotherapy is controversial. This study evaluated the morbidity and modality after self-expandable metallic stent placement in patients with progressive or recurrent esophageal cancer after chemoradiotherapy.
METHODS: A total of 22 patients in whom self-expandable metallic stents were placed because of progressive or recurrent esophageal cancer after chemoradiotherapy were studied.
RESULTS: All 22 patients had dysphagia, and 13 had a tracheoesophageal fistula. After self-expandable metallic stent placement, the mean dysphagia grade improved from 3.5 to 0.9, and tracheoesophageal fistula was successfully managed in all cases. Seventeen patients had T4 stage disease, and among 8 of them with invasion to the aorta, 6 (75%) died of sudden massive hemorrhage. Median survival for these 6 patients was 31 days (range 13-63 days) compared with 67 days (range 4-262 days) for all patients after self-expandable metallic stent placement.
CONCLUSION: Self-expandable metallic stent placement improved dysphagia and was useful for treatment of tracheoesophageal fistula. However, for patients with T4 lesions that invade to the aorta, self-expandable metallic stent placement after chemoradiotherapy should be considered carefully.

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Year:  2003        PMID: 12776036     DOI: 10.1016/s0016-5107(03)70024-8

Source DB:  PubMed          Journal:  Gastrointest Endosc        ISSN: 0016-5107            Impact factor:   9.427


  7 in total

1.  Thoracic spondylodiscitis resulting from proximal migration of an esophageal stent.

Authors:  Steven L Condron; Michel Kahaleh; Vanessa M Shami
Journal:  Dig Dis Sci       Date:  2008-12-05       Impact factor: 3.199

2.  Postchemotherapy expulsion of oesophageal endoluminal stent with vomiting: a rare occurrence.

Authors:  Sameer Gupta; Luv K Kacker
Journal:  BMJ Case Rep       Date:  2012-09-25

3.  Endoscopic stenting and concurrent chemoradiotherapy for advanced esophageal cancer: a case-control study.

Authors:  Xiang-Jun Jiang; Ming-Quan Song; Yong-Ning Xin; Yu-Qiang Gao; Zi-Yu Niu; Zi-Bin Tian
Journal:  World J Gastroenterol       Date:  2012-03-28       Impact factor: 5.742

4.  Endoprosthesis implantation at the pharyngo-esophageal level: problems, limitations and challenges.

Authors:  Efthimios Eleftheriadis; Katerina Kotzampassi
Journal:  World J Gastroenterol       Date:  2006-04-07       Impact factor: 5.742

5.  Management of Tracheoesophageal Fistulas in Adults.

Authors:  Shailendra S. Chauhan; John D. Long
Journal:  Curr Treat Options Gastroenterol       Date:  2004-02

6.  Factors That Affect Stent-Related Complications in Patients with Malignant Obstruction of the Esophagus or Gastric Cardia.

Authors:  Hiroyasu Iwasaki; Takashi Mizushima; Yuta Suzuki; Shigeki Fukusada; Kenta Kachi; Takanori Ozeki; Kaiki Anbe; Hironobu Tsukamoto; Fumihiro Okumura; Takashi Joh; Hitoshi Sano
Journal:  Gut Liver       Date:  2017-01-15       Impact factor: 4.519

7.  Massive hemorrhage following definitive esophageal chemoradiation: teaching case of a fatal aortoesophageal fistula and lessons learned.

Authors:  Gwendolyn J McGinnis; John M Holland; Charles R Thomas; Nima Nabavizadeh
Journal:  Clin Case Rep       Date:  2017-11-07
  7 in total

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