Literature DB >> 12775412

Herpes simplex virus latency-associated transcript gene function.

Jennifer R Kent1, Wen Kang, Cathie G Miller, Nigel W Fraser.   

Abstract

A major area of interest in the study of herpes simplex virus type 1 (HSV-1) involves the persistence of the virus within a latent state in neuronal cells of infected humans. The latency-associated transcripts (LATs) are believed to play a key role during HSV-1 latency. This review will discuss the most recent findings on the involvement of the LAT region with apoptotic pathways and how this relates to other potential functions of the LATs.

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Year:  2003        PMID： 12775412     DOI： 10.1080/13550280390200994

Source DB:  PubMed          Journal:  J Neurovirol        ISSN： 1355-0284            Impact factor:   2.643


  35 in total

1.  Comprehensive quantification of herpes simplex virus latency at the single-cell level.

Authors:  N M Sawtell
Journal:  J Virol       Date:  1997-07       Impact factor: 5.103

2.  A protein encoded by the herpes simplex virus (HSV) type 1 2-kilobase latency-associated transcript is phosphorylated, localized to the nucleus, and overcomes the repression of expression from exogenous promoters when inserted into the quiescent HSV genome.

Authors:  S K Thomas; C E Lilley; D S Latchman; R S Coffin
Journal:  J Virol       Date:  2002-04       Impact factor: 5.103

3.  Quantification of transcripts from the ICP4 and thymidine kinase genes in mouse ganglia latently infected with herpes simplex virus.

Authors:  M F Kramer; D M Coen
Journal:  J Virol       Date:  1995-03       Impact factor: 5.103

4.  A herpes simplex virus type 1 mutant containing a nontransinducing Vmw65 protein establishes latent infection in vivo in the absence of viral replication and reactivates efficiently from explanted trigeminal ganglia.

Authors:  I Steiner; J G Spivack; S L Deshmane; C I Ace; C M Preston; N W Fraser
Journal:  J Virol       Date:  1990-04       Impact factor: 5.103

Review 5.  Modulation of apoptosis during herpes simplex virus infection in human cells.

Authors:  M Aubert; J A Blaho
Journal:  Microbes Infect       Date:  2001-08       Impact factor: 2.700

6.  Herpes simplex virus type 1 latency-associated transcription plays no role in establishment or maintenance of a latent infection in murine sensory neurons.

Authors:  F Sedarati; K M Izumi; E K Wagner; J G Stevens
Journal:  J Virol       Date:  1989-10       Impact factor: 5.103

7.  A herpes simplex virus type 1 latency-associated transcript mutant with increased virulence and reduced spontaneous reactivation.

Authors:  G C Perng; S M Slanina; A Yukht; B S Drolet; W Keleher; H Ghiasi; A B Nesburn; S L Wechsler
Journal:  J Virol       Date:  1999-02       Impact factor: 5.103

8.  Expression of herpes simplex virus type 1 latency-associated transcripts in the trigeminal ganglia of mice during acute infection and reactivation of latent infection.

Authors:  J G Spivack; N W Fraser
Journal:  J Virol       Date:  1988-05       Impact factor: 5.103

9.  Herpes simplex virus latency-associated transcript encodes a protein which greatly enhances virus growth, can compensate for deficiencies in immediate-early gene expression, and is likely to function during reactivation from virus latency.

Authors:  S K Thomas; G Gough; D S Latchman; R S Coffin
Journal:  J Virol       Date:  1999-08       Impact factor: 5.103

Review 10.  Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics.

Authors:  J F Kerr; A H Wyllie; A R Currie
Journal:  Br J Cancer       Date:  1972-08       Impact factor: 7.640
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  20 in total

Review 1.  Peculiarities of herpes simplex virus (HSV) transcription: an overview.

Authors:  Július Rajcáni; Vojvodová Andrea; Rezuchová Ingeborg
Journal:  Virus Genes       Date:  2004-04       Impact factor: 2.332

Review 2.  Herpes simplex virus-based vectors.

Authors:  Robin Lachmann
Journal:  Int J Exp Pathol       Date:  2004-10       Impact factor: 1.925

3.  Cellular stress rather than stage of the cell cycle enhances the replication and plating efficiencies of herpes simplex virus type 1 ICP0- viruses.

Authors:  Ryan M Bringhurst; Priscilla A Schaffer
Journal:  J Virol       Date:  2006-05       Impact factor: 5.103

4.  A Stronger Transcription Regulatory Circuit of HIV-1C Drives the Rapid Establishment of Latency with Implications for the Direct Involvement of Tat.

Authors:  Sutanuka Chakraborty; Manisha Kabi; Udaykumar Ranga
Journal:  J Virol       Date:  2020-09-15       Impact factor: 5.103

5.  Virological and molecular biological evidence supporting herpes simplex virus type 1 corneal latency.

Authors:  Shiro Higaki; Masahiko Fukuda; Yoshikazu Shimomura
Journal:  Jpn J Ophthalmol       Date:  2015-01-17       Impact factor: 2.447

6.  Herpes simplex virus type 2 (HSV-2) establishes latent infection in a different population of ganglionic neurons than HSV-1: role of latency-associated transcripts.

Authors:  Todd P Margolis; Yumi Imai; Li Yang; Vicky Vallas; Philip R Krause
Journal:  J Virol       Date:  2006-12-06       Impact factor: 5.103

7.  The herpes simplex virus type 1 BgKL variant, unlike the BgOL variant, shows a higher association with orolabial infection than with infections at other sites, supporting the variant-dispersion-replacement hypothesis.

Authors:  Shigeru Ozawa; Hiroyuki Eda; Yasuyuki Ishii; Fumihiko Ban; Toshiyuki Funabashi; Seiichiro Hata; Kozaburo Hayashi; Hiroki Iga; Takao Ikushima; Hiroaki Ishiko; Tomoo Itagaki; Rinji Kawana; Shunsaku Kobayashi; Takeo Ogino; Tsuyoshi Sekizawa; Yoshikazu Shimomura; Hiroshi Shiota; Ryoichi Mori; Takashi Nakakita; Yoshio Numazaki; Yoshikatsu Ozaki; Shigeru Yamamoto; Kamesaburo Yoshino; Kazuo Yanagi
Journal:  J Clin Microbiol       Date:  2007-05-02       Impact factor: 5.948

8.  Investigation of the mechanism by which herpes simplex virus type 1 LAT sequences modulate preferential establishment of latent infection in mouse trigeminal ganglia.

Authors:  Yumi Imai; Kathleen Apakupakul; Philip R Krause; William P Halford; Todd P Margolis
Journal:  J Virol       Date:  2009-06-03       Impact factor: 5.103

Review 9.  Update on emerging antivirals for the management of herpes simplex virus infections: a patenting perspective.

Authors:  Aswani D Vadlapudi; Ramya K Vadlapatla; Ashim K Mitra
Journal:  Recent Pat Antiinfect Drug Discov       Date:  2013-04

10.  Neurons versus herpes simplex virus: the innate immune interactions that contribute to a host-pathogen standoff.

Authors:  Pamela C Rosato; David A Leib
Journal:  Future Virol       Date:  2015-06       Impact factor: 1.831
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