Literature DB >> 12774918

Diffuse large B-cell lymphoma: insights gained from gene expression profiling.

Izidore S Lossos1, Ronald Levy.   

Abstract

Analysis of global gene expression with DNA microarrays has great potential to improve the understanding of tumorigenesis advance tumor diagnosis and classification, and affect cancer treatment. Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's lymphoma. However, we now realize that the disease is extremely heterogeneous. This review summarizes the progress in understanding DLBCL that has been made as a result of the application of gene expression profiling.

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Year:  2003        PMID: 12774918     DOI: 10.1007/bf02982638

Source DB:  PubMed          Journal:  Int J Hematol        ISSN: 0925-5710            Impact factor:   2.490


  44 in total

1.  Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning.

Authors:  Margaret A Shipp; Ken N Ross; Pablo Tamayo; Andrew P Weng; Jeffery L Kutok; Ricardo C T Aguiar; Michelle Gaasenbeek; Michael Angelo; Michael Reich; Geraldine S Pinkus; Tane S Ray; Margaret A Koval; Kim W Last; Andrew Norton; T Andrew Lister; Jill Mesirov; Donna S Neuberg; Eric S Lander; Jon C Aster; Todd R Golub
Journal:  Nat Med       Date:  2002-01       Impact factor: 53.440

Review 2.  Germinal centers.

Authors:  I C MacLennan
Journal:  Annu Rev Immunol       Date:  1994       Impact factor: 28.527

3.  MYC rearrangements in histologically progressed follicular lymphomas.

Authors:  T Yano; E S Jaffe; D L Longo; M Raffeld
Journal:  Blood       Date:  1992-08-01       Impact factor: 22.113

4.  Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas.

Authors:  I S Lossos; A A Alizadeh; M B Eisen; W C Chan; P O Brown; D Botstein; L M Staudt; R Levy
Journal:  Proc Natl Acad Sci U S A       Date:  2000-08-29       Impact factor: 11.205

Review 5.  The NF-kappa B/Rel and I kappa B gene families: mediators of immune response and inflammation.

Authors:  F G Wulczyn; D Krappmann; C Scheidereit
Journal:  J Mol Med (Berl)       Date:  1996-12       Impact factor: 4.599

6.  p16(INK4a) gene inactivation by deletions, mutations, and hypermethylation is associated with transformed and aggressive variants of non-Hodgkin's lymphomas.

Authors:  M Pinyol; F Cobo; S Bea; P Jares; I Nayach; P L Fernandez; E Montserrat; A Cardesa; E Campo
Journal:  Blood       Date:  1998-04-15       Impact factor: 22.113

7.  Morphologic transformation of follicular lymphoma is associated with somatic mutation of the translocated Bcl-2 gene.

Authors:  A Matolcsy; P Casali; R A Warnke; D M Knowles
Journal:  Blood       Date:  1996-11-15       Impact factor: 22.113

8.  Cluster analysis and display of genome-wide expression patterns.

Authors:  M B Eisen; P T Spellman; P O Brown; D Botstein
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-08       Impact factor: 11.205

9.  A predictive model for aggressive non-Hodgkin's lymphoma.

Authors: 
Journal:  N Engl J Med       Date:  1993-09-30       Impact factor: 91.245

10.  Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells.

Authors:  R E Davis; K D Brown; U Siebenlist; L M Staudt
Journal:  J Exp Med       Date:  2001-12-17       Impact factor: 14.307

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  4 in total

1.  CD5+ diffuse large B-cell lymphoma consists of germline cases and hypermutated cases in the immunoglobulin heavy chain gene variable region.

Authors:  Naoya Nakamura; Shigeo Nakamura; Motoko Yamaguchi; Ryo Ichinohasama; Tadashi Yoshino; Tetsuo Kuze; Yoshikazu Sasaki; Sachiko Yoshida; Masafumi Abe
Journal:  Int J Hematol       Date:  2005-01       Impact factor: 2.490

2.  A unified 35-gene signature for both subtype classification and survival prediction in diffuse large B-cell lymphomas.

Authors:  Yu-Dong Cai; Tao Huang; Kai-Yan Feng; Lele Hu; Lu Xie
Journal:  PLoS One       Date:  2010-09-13       Impact factor: 3.240

3.  Primary mediastinal large B-cell lymphoma: a single-institution clinical study in Japan.

Authors:  Naohiro Sekiguchi; Junko Nishimoto; Kazuki Tanimoto; Shigeru Kusumoto; Yasushi Onishi; Takashi Watanabe; Yukio Kobayashi; Hisao Asamura; Yoshikazu Kagami; Yoshihiro Matsuno; Kensei Tobinai
Journal:  Int J Hematol       Date:  2004-06       Impact factor: 2.490

4.  The CXCR4-CXCL12-Axis Is of Prognostic Relevance in DLBCL and Its Antagonists Exert Pro-Apoptotic Effects In Vitro.

Authors:  Katrin Pansy; Julia Feichtinger; Barbara Ehall; Barbara Uhl; Miriam Sedej; David Roula; Beata Pursche; Axel Wolf; Manuel Zoidl; Elisabeth Steinbauer; Verena Gruber; Hildegard T Greinix; Katharina T Prochazka; Gerhard G Thallinger; Akos Heinemann; Christine Beham-Schmid; Peter Neumeister; Tanja M Wrodnigg; Karoline Fechter; Alexander Ja Deutsch
Journal:  Int J Mol Sci       Date:  2019-09-24       Impact factor: 5.923

  4 in total

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