Literature DB >> 12774399

[Determination of trigonelline in Trigonella foenum-graecum by HPLC].

Huai-qing Zhao1, Yan Qu, Xue-ya Wang, Hong-jian Zhang, Fa-mei Li, Hattori Masao.   

Abstract

OBJECTIVE: A HPLC method is established to determine the content of trigonelline in Trigonella foenum-graecum.
METHOD: The medicinal material was extracted by petholeum ether-ethanol. Asahipak NH2P-50 column was used, mobilephase consisted of acetonitrile-water(75:25) and detection wavelength was set at UV 265 nm. RESULT: The standard curve was linear in the range of 3.68-73.60 micrograms.mL-1 with the correlation coefficient of 0.9999. The average recovery rate and RSD were 97.4% and 1.83% (n = 6) respectively.
CONCLUSION: It provides scientific indexes for quality control of T. foenum-graecum.

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Year:  2002        PMID: 12774399

Source DB:  PubMed          Journal:  Zhongguo Zhong Yao Za Zhi        ISSN: 1001-5302


  3 in total

1.  Raf/ERK/Nrf2 signaling pathway and MMP-7 expression involvement in the trigonelline-mediated inhibition of hepatocarcinoma cell migration.

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Journal:  Food Nutr Res       Date:  2015-12-22       Impact factor: 3.894

2.  A validated RP-HPLC method for quantitation of trigonelline from herbal formulations containing Trigonella foenum-graecum (L.) seeds.

Authors:  Sunita Shailajan; Sasikumar Menon; Ashish Singh; Mandar Mhatre; Neelam Sayed
Journal:  Pharm Methods       Date:  2011-07

3.  Fenugreek seed extract treats peripheral neuropathy in pyridoxine induced neuropathic mice.

Authors:  Farshad Homayouni Moghadam; Behzad Vakili-Zarch; Mohammad Shafiee; Azam Mirjalili
Journal:  EXCLI J       Date:  2013-02-25       Impact factor: 4.068

  3 in total

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