OBJECTIVE: To investigate the effects and the related mechanisms of the components of Dang-Gui-Bu-Xue decoction (DGBXD) on improving blood deficiency. METHOD: The effects of promoting hematopoietic function were observed with the blood difficient model mice, by giving components of DGBXD. RBC, WBC, reticulocytes and bone marrow nucleated cells (BMNC) were determined. The components of DGBXD on proliferation of BMNC and on clony forming unit (CFU) were also determined. RESULT: The components of DGBXD remarkably increased the quantity of RBC, WBC, and BMNC. Some of the components promoted the proliferation of BMNC and increased the quantity of CFU-Mix. Among them, polysaccharide of angelica was most potent. CONCLUSION: The studies show that the extracts and some components of DGBXD can promote the hemopoietic function system of the model mice, and they exert the effects in a comprehensive way.
OBJECTIVE: To investigate the effects and the related mechanisms of the components of Dang-Gui-Bu-Xue decoction (DGBXD) on improving blood deficiency. METHOD: The effects of promoting hematopoietic function were observed with the blood difficient model mice, by giving components of DGBXD. RBC, WBC, reticulocytes and bone marrow nucleated cells (BMNC) were determined. The components of DGBXD on proliferation of BMNC and on clony forming unit (CFU) were also determined. RESULT: The components of DGBXD remarkably increased the quantity of RBC, WBC, and BMNC. Some of the components promoted the proliferation of BMNC and increased the quantity of CFU-Mix. Among them, polysaccharide of angelica was most potent. CONCLUSION: The studies show that the extracts and some components of DGBXD can promote the hemopoietic function system of the model mice, and they exert the effects in a comprehensive way.
Authors: Roy C Y Choi; Qiu T Gao; Anna W H Cheung; Judy T T Zhu; Faye T C Lau; Jun Li; Winnie Z M Li; Glanice K Y Chu; Ran Duan; Jerry K H Cheung; An W Ding; Kui J Zhao; Tina T X Dong; Karl W K Tsim Journal: Evid Based Complement Alternat Med Date: 2011-06-18 Impact factor: 2.629
Authors: Qiutao Gao; Jun Li; Jerry Ka Hei Cheung; Jinao Duan; Anwei Ding; Anna Wing Han Cheung; Kuijun Zhao; Winnie Zhuoming Li; Tina Tingxia Dong; Karl Wah Keung Tsim Journal: Chin Med Date: 2007-11-29 Impact factor: 5.455
Authors: Crystal Y Q Du; Roy C Y Choi; Ken Y Z Zheng; Tina T X Dong; David T W Lau; Karl W K Tsim Journal: PLoS One Date: 2013-11-11 Impact factor: 3.240