| Literature DB >> 127743 |
Abstract
A convenient microtest is described which utilizes antibody-mediated release of [14C]nicotinamide ([14C]NA) from target cells for the detection of cell surface antigens. This test is considerably more sensitive and faster than the widely used 51Cr release test because most of the [14C]NA is rapidly released from the target cells in the initial phase of membrane permeability changes induced by activated complement, as distinct from the colloid osmotic phase of complement-mediated cytolysis.Entities:
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Year: 1975 PMID: 127743 PMCID: PMC1445986
Source DB: PubMed Journal: Immunology ISSN: 0019-2805 Impact factor: 7.397