Literature DB >> 1277177

Approaches to prevention of epithelial cancer during the preneoplastic period.

M B Sporn.   

Abstract

The development of epithelial cancer is a disease process that takes many years to reach its final, invasive stage in humans. This disease process has the potential to be controlled by physiological or pharmacological means during its preneoplastic stages. Mechanisms whereby the progression of preneoplastic lesions can be stabilized, arrested, or reversed are discussed. Pharmacological enhancement of such mechanisms by synthetic vitamin A analogs (retinoids) offers a possible means for prevention of invasive epithelial cancer.

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Year:  1976        PMID： 1277177

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  78 in total

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6.  Adverse effects of highdose vitamin A during radiotherapy.

Authors:  W J Issing; M Busch; B Schymura
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Review 7.  Clinical development of fenretinide as an antineoplastic drug: Pharmacology perspectives.

Authors:  Jason P Cooper; C Patrick Reynolds; Hwangeui Cho; Min H Kang
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8.  Chemoprevention activity of dipyridamole in the MMTV-PyMT transgenic mouse model of breast cancer.

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Review 9.  Silicon micro- and nanofabrication for medicine.

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Journal:  Adv Healthc Mater       Date:  2013-04-15       Impact factor: 9.933

Review 10.  The hallmarks of premalignant conditions: a molecular basis for cancer prevention.

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