| Literature DB >> 12770583 |
Kristina Jenett-Siems1, Carola Kraft, Karsten Siems, Jasmin Jakupovic, Pablo N Solis, Mahabir P Gupta, Ulrich Bienzle.
Abstract
The phytochemical investigation of the leaves of Siparuna pauciflora yielded three novel sesquiterpenoids: the germacrane sipaucin A, the elemane sipaucin B and sipaucin C, comprising a new type of carbon skeleton. In addition, four known aporphine alkaloids-nor-boldine, boldine, laurotetanine, and N-methyl-laurotetanine-were obtained. The evaluation of the antiplasmodial activity of the isolated compounds against two strains of Plasmodium falciparum (PoW, Dd2) showed a moderate activity of nor-boldine.Entities:
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Year: 2003 PMID： 12770583 DOI： 10.1016/s0031-9422(03)00098-0
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072