| Literature DB >> 12770521 |
N de la Rocha1, A O M María, J C Gianello, L Pelzer.
Abstract
The effects of 2',4'-dihydroxychalcone and 2',4'-dihydroxy-3'-methoxychalcone from Zuccagnia punctata Cav. (Fabaceae) and melatonin administration on ethanol-induced gastroduodenal injury were investigated in rats. Both chalcones showed significant preventive effects in treatment with melatonin previous to the necrotising agent. These effects could be due, in part, to the radical scavenging activity of the melatonin.Entities:
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Year: 2003 PMID: 12770521 DOI: 10.1016/s1043-6618(03)00063-x
Source DB: PubMed Journal: Pharmacol Res ISSN: 1043-6618 Impact factor: 7.658